ACAP1

Gene Symbol ACAP1
Entrez Gene 9744
Alt Symbol CENTB1
Species Human
Gene Type protein-coding
Description ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
Other Description Arf GAP with coiled coil, ANK repeat and PH domains 1|arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1|centaurin, beta 1|centaurin-beta-1|cnt-b1
Swissprots Q53XN9 Q15027
Accessions EAW90209 EAW90210 Q15027 AA356620 BC018543 AAH18543 BT009788 AAP88790 D30758 BAA06418 DQ891719 ABM82645 XM_005256878 XP_005256935 XR_243574 XR_429827 NM_014716 NP_055531
Function GTPase-activating protein (GAP) for ADP ribosylation factor 6 (ARF6) required for clathrin-dependent export of proteins from recycling endosomes to trans-Golgi network and cell surface. Required for regulated export of ITGB1 from recycling endosomes to the cell surface and ITGB1-dependent cell migration. {ECO:0000269|PubMed:11062263, ECO:0000269|PubMed:16256741, ECO:0000269|PubMed:17398097, ECO:0000269|PubMed:17664335, ECO:0000269|PubMed:22645133}.
Subcellular Location Recycling endosome membrane {ECO:0000269|PubMed:16256741}; Peripheral membrane protein {ECO:0000269|PubMed:16256741}; Cytoplasmic side {ECO:0000269|PubMed:16256741}.
Tissue Specificity Highest level in lung and spleen. Low level in heart, kidney, liver and pancreas. {ECO:0000269|PubMed:11062263}.
Top Pathways Endocytosis

ACAP1 (B-11) - sc-376574 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
ACAP1 (B-11): sc-376574. Western blot analysis of ACAP1 expression in Jurkat whole cell lysate.

ACAP1 (K-19) - sc-47780 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
ACAP1 (K-19): sc-47780. Western blot analysis of ACAP1 expression in non-transfected: sc-110760 (A) and human ACAP1 transfected: sc-113342 (B) 293 whole cell lysates.

ACAP1 (E-13) - sc-49593 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
ACAP1 (E-13): sc-49593. Western blot analysis of ACAP1 expression in non-transfected: sc-110760 (A) and human ACAP1 transfected: sc-113342 (B) 293 whole cell lysates.

ACAP1 (G-4) - sc-137172 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
ACAP1 (G-4): sc-137172. Western blot analysis of ACAP1 expression in non-transfected: sc-110760 (A) and human ACAP1 transfected: sc-113342 (B) 293 whole cell lysates.

ACAP1 (H-155) - sc-292305 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
ACAP1 (H-155): sc-292305. Western blot analysis of ACAP1 expression in non-transfected: sc-110760 (A) and human ACAP1 transfected: sc-113342 (B) 293 whole cell lysates.

ACAP1 (N-16) - sc-47781 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
ACAP1 (N-16): sc-47781. Western blot analysis of ACAP1 expression in HeLa whole cell lysate.

ACAP1 (N-19) - sc-47782 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-CENTB1 (phospho S554) antibody - ab111378 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ab111378 at 1/50 dilution staining CENTB1 in paraffin-embedded Human Lung carcinoma tissue by Immunohistochemistry. The image on the right is treated with the synthesized phosphopeptide.

Anti-CENTB1 antibody - ab107039 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-CENTB1 antibody (ab107039) at 1/100 dilution + ZR-75-1 cell lysate at 35 µg

Anti-CENTB1 antibody - ab89766 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-CENTB1 antibody (ab89766) at 1 µg/ml + Human spleen tissue lysate at 50 µg

Anti-CENTB1 antibody - ab15903 from Abcam

Prices $370.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-CENTB1 / ACAP1 Antibody (aa520-560) - LS-C143785 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-CENTB1 / ACAP1 Antibody (aa678-740) - LS-C185895 from LifeSpan Bioscience

Prices $245.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-CENTB1 / ACAP1 Antibody (aa103-132, AP) - LS-C250630 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CENTB1 / ACAP1 Antibody (aa103-132, Biotin) - LS-C250632 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CENTB1 / ACAP1 Antibody (aa103-132, APC) - LS-C250631 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CENTB1 / ACAP1 Antibody (aa103-132, FITC) - LS-C250633 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CENTB1 / ACAP1 Antibody (aa520-560) - LS-C148567 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of ACAP1 in K562 cell lysate in the 1) absence and 2) presence of immunizing peptide using LS-C148567 at 1.0 ug/ml. Goat anti-rabbit Ig HRP secondary antibody, and PicoTect ECL substrate solution, were used for this test.

Anti-CENTB1 / ACAP1 Antibody (aa103-132, Azide-free, HRP) - LS-C250634 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CENTB1 / ACAP1 Antibody (aa103-132, PE) - LS-C250635 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CENTB1 / ACAP1 Antibody (phospho-Ser554) - LS-C286247 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-CENTB1 / ACAP1 Antibody - LS-C306046 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-CENTB1 / ACAP1 Antibody (aa103-132) - LS-C155912 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
ACAP1 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human spleen tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

Anti-CENTB1 / ACAP1 Antibody (aa103-132) - LS-C319271 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CENTB1 / ACAP1 Antibody (C-Terminus) IHC-plus™ - LS-B2280 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-ACAP1 / CENTB1 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2280 concentration 5 ug/ml.
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