ACAP1

Gene Symbol ACAP1
Entrez Gene 9744
Alt Symbol CENTB1
Species Human
Gene Type protein-coding
Description ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
Other Description Arf GAP with coiled coil, ANK repeat and PH domains 1|arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1|centaurin, beta 1|centaurin-beta-1|cnt-b1
Swissprots Q53XN9 Q15027
Accessions EAW90209 EAW90210 Q15027 AA356620 BC018543 AAH18543 BT009788 AAP88790 D30758 BAA06418 DQ891719 ABM82645 XM_005256878 XP_005256935 XR_243574 XR_429827 NM_014716 NP_055531
Function GTPase-activating protein (GAP) for ADP ribosylation factor 6 (ARF6) required for clathrin-dependent export of proteins from recycling endosomes to trans-Golgi network and cell surface. Required for regulated export of ITGB1 from recycling endosomes to the cell surface and ITGB1-dependent cell migration. {ECO:0000269|PubMed:11062263, ECO:0000269|PubMed:16256741, ECO:0000269|PubMed:17398097, ECO:0000269|PubMed:17664335, ECO:0000269|PubMed:22645133}.
Subcellular Location Recycling endosome membrane {ECO:0000269|PubMed:16256741}; Peripheral membrane protein {ECO:0000269|PubMed:16256741}; Cytoplasmic side {ECO:0000269|PubMed:16256741}.
Tissue Specificity Highest level in lung and spleen. Low level in heart, kidney, liver and pancreas. {ECO:0000269|PubMed:11062263}.
Top Pathways Endocytosis

Human CENTB1 full length protein - ab132164 from Abcam

Category Protein
Source Wheat germ
Species Human
12.5% SDS-PAGE analysis of ab132164 stained with Coomassie Blue.

Human CENTB1 peptide - ab23280 from Abcam

Category Peptide
Species Human

Human CENTB1 protein fragment - ab160635 from Abcam

Category Protein
Source Wheat germ
Species Human
ab160635 on a 12.5% SDS-PAGE stained with Coomassie Blue.

CENTB1 / ACAP1 Antibody Blocking Peptide - LS-E782 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

CENTB1 / ACAP1 Antibody Blocking Peptide - LS-E25612 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Recombinant Human CENTB1 Protein - H00009744-P01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

CENTB1 Partial Recombinant Protein - H00009744-Q01 from Novus Biologicals

Category Protein
Prices $369.00
Sizes 10 µg
Species Human

ACAP1-Antibody-N-term-Blocking-peptide - BP11134a from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

CENTB1 Peptide - AC21-0443-P from Abcore

Category Peptide
Prices $160.00
Sizes 100 µg

ACAP1 / CENTB1 - H00009744-P01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Species Human

ACAP1 / CENTB1 - H00009744-P01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Species Human

ACAP1 / CENTB1 - H00009744-Q01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Source in vitro transl.
Species Human

ACAP1 / CENTB1 - H00009744-Q01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Source in vitro transl.
Species Human

ACAP1 Peptide - 45-191P from ProSci

Category Peptide
Prices $175.00
Sizes 100 µg
Species Human

ACAP1 fusion protein - ag14068 from Proteintech Group

Category Protein
Source E. coli-derived, PKG
Species Human

ACAP1 fusion protein - Ag14254 from Proteintech Group

Category Protein
Source E. coli -derived, PET28a
Species Human

Recombinant Human Arf-GAP with coiled-coil, ANK repeat and PH domain-containing - CSB-YP622985HU CSB-EP622985HU CSB-BP622985HU CSB-MP622985HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

ACAP1 / CENTB1 - TP303724 from Acris Antibodies

Category Protein
Prices $680.00
Sizes 20 µg
Source HEK293 cells
Species Human
ACAP1 / CENTB1

Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1(ACAP1) , Recombinant Protein - MBS1356972 from MyBioSource

Category Protein
Prices $2,670.00, $2,670.00, $3,090.00, $3,090.00
Sizes 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human

CENTB1/ACAP1, Peptide - MBS425537 from MyBioSource

Category Peptide
Prices $175.00
Sizes 100 µg
Species Human, Mouse, Rat, Dog, Bovine

CENTB1 Protein - NBP2-14256PEP from Novus Biologicals

Category Protein
Prices $209.00
Sizes 100 µl
Species Human

CENTB1 Recombinant Protein Antigen - NBP2-55692PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human

ACAP1 Immunizing peptide - orb17568 from Biorbyt

Category Peptide
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