Gene Symbol | ERCC4 |
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Entrez Gene | 2072 |
Alt Symbol | ERCC11, FANCQ, RAD1, XPF |
Species | Human |
Gene Type | protein-coding |
Description | excision repair cross-complementation group 4 |
Other Description | DNA excision repair protein ERCC-4|DNA repair endonuclease XPF|DNA repair protein complementing XP-F cells|excision repair cross-complementing rodent repair deficiency, complementation group 4|excision-repair, complementing defective, in Chinese hamster|xeroderma pigmentosum group F-complementing protein|xeroderma pigmentosum, complementation group F |
Swissprots | Q8TD83 A5PKV6 Q92889 O00140 A8K111 |
Accessions | AAB50174 AAL91593 EAW85117 EAW85118 Q92889 AI470593 AK289726 BAF82415 AK301930 BAG63350 AK308341 BC020741 AAH20741 BC142631 AAI42632 BC160102 AAI60102 U64315 AAB07689 XM_011522424 XP_011520726 XM_011522425 XP_011520727 XM_011522426 XP_011520728 XM_011522427 XP_011520729 XR_932805 NM_005236 NP_005227 |
Function | Catalytic component of a structure-specific DNA repair endonuclease responsible for the 5-prime incision during DNA repair. Involved in homologous recombination that assists in removing interstrand cross-link. {ECO:0000269|PubMed:19596235}. |
Subcellular Location | Nucleus {ECO:0000305}. |
Top Pathways | Nucleotide excision repair, Fanconi anemia pathway |
ERCC4 / XPF Antibody Blocking Peptide - LS-E21319 from LifeSpan Bioscience
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RAD1 Antibody Blocking Peptide - LS-E3835 from LifeSpan Bioscience
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RAD1 Antibody Blocking Peptide - LS-E21082 from LifeSpan Bioscience
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Rad1 Recombinant Protein - H00005810-P01 from Novus Biologicals
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Rad1 Partial Recombinant Protein - H00005810-Q01 from Novus Biologicals
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Recombinant Human Rad1 Protein - NBP1-45298 from Novus Biologicals
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Human RAD1 protein - orb81302 from Biorbyt
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ERCC4 peptide - orb217260 from Biorbyt
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ERCC4 Blocking Peptide - 33R-2974 from Fitzgerald
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RAD1 Blocking Peptide - 33R-4182 from Fitzgerald
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RAD1 protein (His tag) - 80R-1407 from Fitzgerald
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ERCC4 Blocking Peptide - abx062591 from Abbexa
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RAD1 Blocking Peptide - abx064195 from Abbexa
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RAD1, Human Recombinant - 228-13308-1 from RayBiotech
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Recombinant Human RAD1 - 228-13308-2 from RayBiotech
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Recombinant Human RAD1 - 228-13308-3 from RayBiotech
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RAD1 Human Protein - GWB-BSP597 from Genway Biotech
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Recombinant Xeroderma Pigmentosum, Complementation Group F (XPF) - RPE731Hu01 from Uscn Life Science Inc.
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ERCC4 Blocking Peptide - CBP1397 from Cohesion Biosciences
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ERCC4 (A822) Peptide - BS2430P from Bioworld Technology
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Recombinant Xeroderma Pigmentosum, Complementation Group F (XPF) - RPE731Hu01 from Cloud-clone
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Recombinant Human DNA repair endonuclease XPF(ERCC4) ,partial - CSB-YP849795HU CSB-EP849795HU CSB-BP849795HU CSB-MP849795HU from Cusabio
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ERCC4 Protein - abx163293 from Abbexa
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RAD1 Protein (Recombinant) - abx262902 from Abbexa
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ERCC4 - TP323300 from Acris Antibodies
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