ERCC4

Gene Symbol	ERCC4
Entrez Gene	2072
Alt Symbol	ERCC11, FANCQ, RAD1, XPF
Species	Human
Gene Type	protein-coding
Description	excision repair cross-complementation group 4
Other Description	DNA excision repair protein ERCC-4|DNA repair endonuclease XPF|DNA repair protein complementing XP-F cells|excision repair cross-complementing rodent repair deficiency, complementation group 4|excision-repair, complementing defective, in Chinese hamster|xeroderma pigmentosum group F-complementing protein|xeroderma pigmentosum, complementation group F
Swissprots	Q8TD83 A5PKV6 Q92889 O00140 A8K111
Accessions	AAB50174 AAL91593 EAW85117 EAW85118 Q92889 AI470593 AK289726 BAF82415 AK301930 BAG63350 AK308341 BC020741 AAH20741 BC142631 AAI42632 BC160102 AAI60102 U64315 AAB07689 XM_011522424 XP_011520726 XM_011522425 XP_011520727 XM_011522426 XP_011520728 XM_011522427 XP_011520729 XR_932805 NM_005236 NP_005227
Function	Catalytic component of a structure-specific DNA repair endonuclease responsible for the 5-prime incision during DNA repair. Involved in homologous recombination that assists in removing interstrand cross-link. {ECO:0000269|PubMed:19596235}.
Subcellular Location	Nucleus {ECO:0000305}.
Top Pathways	Nucleotide excision repair, Fanconi anemia pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

XPF CRISPR/Cas9 KO Plasmid (h) - sc-401692 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

XPF HDR Plasmid (h) - sc-401692-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

XPF Double Nickase Plasmid (h) - sc-401692-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

XPF Double Nickase Plasmid (h2) - sc-401692-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

XPF CRISPR Activation Plasmid (h) - sc-401692-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

XPF CRISPR Activation Plasmid (h2) - sc-401692-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

XPF Lentiviral Activation Particles (h) - sc-401692-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

XPF Lentiviral Activation Particles (h2) - sc-401692-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

XPF siRNA (h) - sc-36855 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

XPF shRNA Plasmid (h) - sc-36855-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

XPF shRNA (h) Lentiviral Particles - sc-36855-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

Rad1 RNAi - H00005810-R01V from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

XPF RNAi - H00002072-R01 from Novus Biologicals Category siRNA Prices $409.00 Sizes 20 nmol Species Reactivities Human

Rad1 RNAi - H00005810-R01 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU154291 from Sigma-Aldrich Category siRNA Prices $250.00 Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN7951 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7951 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

ERCC4 siRNA (Human) - CRH1447 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

ERCC4 - MBS8227030 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human ERCC4(NM_005236.2) - SHH038225 from Creative biogene Category siRNA Species Reactivities Human

Human ERCC4 siRNA - orb261949 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

ERCC4 shRNA Plasmid (Human) - CHH1447 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

ERCC4 miRNA 3'UTR clone - MiUTR1H-03290 from Creative biogene Species Reactivities Human

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