FASLG

Gene Symbol	FASLG
Entrez Gene	356
Alt Symbol	ALPS1B, APT1LG1, APTL, CD178, CD95-L, CD95L, FASL, TNFSF6
Species	Human
Gene Type	protein-coding
Description	Fas ligand (TNF superfamily, member 6)
Other Description	CD95 ligand|apoptosis (APO-1) antigen ligand 1|apoptosis antigen ligand|fas antigen ligand|tumor necrosis factor ligand superfamily member 6
Swissprots	Q9BZP9 P48023
Accessions	AAB96632 AAC39768 ABK41922 BAA32542 CAX86839 CBX53895 CCA94585 EAW90935 EAW90936 P48023 AF288573 AAG60017 AK314874 BAG37389 AY225406 AAO43991 AY858799 AAX49569 BC017502 AAH17502 D38122 BAA07320 DA916336 DQ893466 ABM84392 DQ896147 ABM87146 U08137 AAC50071 U11821 AAC50124 X89102 CAA61474 NM_000639 NP_000630 NM_001302746 NP_001289675
Function	Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. May be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. Binding to the decoy receptor TNFRSF6B/DcR3 modulates its effects. {ECO:0000269|PubMed:17557115}.
Subcellular Location	FasL intracellular domain: Nucleus. Note=The FasL ICD cytoplasmic form is translocated into the nucleus.
Top Pathways	PI3K-Akt signaling pathway, Herpes simplex infection, Chagas disease (American trypanosomiasis), Non-alcoholic fatty liver disease (NAFLD), Proteoglycans in cancer

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Fas Ligand (APTL) Human ELISA Kit - ab100515 from Abcam Category ELISA Kit Prices $489.00 Sizes 1 x 96 tests Sensitivity < 2 pg/ml Range 1.37 pg/ml - 1000 pg/ml

Fas Ligand Human ELISA Set (without plates) - ab83703 from Abcam Prices $537.00, $620.00 Sizes 5 x 96 tests, 10 x 96 tests Sensitivity < 44 pg/ml Range 62.5 pg/ml - 2000 pg/ml

Fas Ligand Human Elispot Kit - ab46605 from Abcam Category ELISA Kit Prices $937.00, $1,563.00 Sizes 5 x 96 tests, 10 x 96 tests

Fas Ligand Human Elispot Kit - ab62920 from Abcam Category ELISA Kit Prices $339.00, $937.00 Sizes 1 x 96 tests, 5 x 96 tests

Fas Ligand Human Elispot Kit (Reagents for 10 x 96 tests, without plates) - ab46630 from Abcam Category ELISA Kit Prices $1,021.00 Sizes 10 x 96 tests

Fas Ligand Human Elispot Kit (without plates) - ab46577 from Abcam Category ELISA Kit Prices $729.00, $1,021.00, $1,359.00, $1,614.00 Sizes 5 x 96 tests, 10 x 96 tests, 15 x 96 tests, 20 x 96 tests

FAS Ligand (CD95L) Human ELISA Kit - ab45892 from Abcam Category ELISA Kit Prices $489.00, $734.00 Sizes 1 x 96 tests, 2 x 96 tests Sensitivity < 12 pg/ml Range 62.5 pg/ml - 2000 pg/ml

Rat FASLG / Fas Ligand ELISA Kit (Sandwich ELISA) - LS-F2830 from LifeSpan Bioscience Category ELISA Kit Prices $530.00 Sizes 1 plate Sensitivity 10 pg/ml Range 1.371-333.3 pg/ml

Human FASLG / Fas Ligand ELISA Kit (Sandwich ELISA) - LS-F2420 from LifeSpan Bioscience Category ELISA Kit Prices $590.00 Sizes 1 plate Sensitivity 15.6 pg/ml Range 1.371-333.3 pg/ml

Mouse FASLG / Fas Ligand ELISA Kit (Sandwich ELISA) - LS-F2421 from LifeSpan Bioscience Category ELISA Kit Prices $570.00 Sizes 1 plate Sensitivity 10 pg/ml Range 1.371-333.3 pg/ml

Human FASLG / Fas Ligand ELISA Kit (Sandwich ELISA) - LS-F3992 from LifeSpan Bioscience Category ELISA Kit Prices $470.00 Sizes 1 plate Sensitivity 6.5 pg/ml Range 1.371-333.3 pg/ml

Mouse FASLG / Fas Ligand ELISA Kit (Sandwich ELISA) - LS-F3993 from LifeSpan Bioscience Category ELISA Kit Prices $470.00 Sizes 1 plate Sensitivity 0.061 ng/ml Range 1.371-333.3 pg/ml

Mouse FASLG / Fas Ligand ELISA Kit (Sandwich ELISA) - LS-F381 from LifeSpan Bioscience Category ELISA Kit Prices $670.00, $1,190.00, $2,570.00 Sizes 1 plate, 2 plate, 5 plate Sensitivity 8.19 pg/ml Range 1.371-333.3 pg/ml

Mouse/Human FASLG / Fas Ligand ELISA Kit (Cell-Based ELISA) - LS-F1985 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate Range 1.371-333.3 pg/ml

Human FASLG / Fas Ligand ELISA Kit (Sandwich ELISA) - LS-F82 from LifeSpan Bioscience Category ELISA Kit Prices $460.00, $840.00, $1,960.00 Sizes 1 plate, 2 plate, 5 plate Sensitivity 1.371 pg/ml Range 1.371-333.3 pg/ml

Rat FASLG / Fas Ligand ELISA Kit (Sandwich ELISA) - LS-F310 from LifeSpan Bioscience Category ELISA Kit Prices $670.00, $1,190.00, $2,570.00 Sizes 1 plate, 2 plate, 5 plate Sensitivity 529.1 pg/ml Range 1.371-333.3 pg/ml

Human FASLG / Fas Ligand ELISA Kit (Sandwich ELISA) - LS-F634 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate Range 1.371-333.3 pg/ml

Human FASLG / Fas Ligand ELISA Kit (Sandwich ELISA) - LS-F12802 from LifeSpan Bioscience Category ELISA Kit Prices $530.00 Sizes 1 plate Sensitivity 31.2 Range 1.371-333.3 pg/ml

Rat FASLG / Fas Ligand ELISA Kit (Sandwich ELISA) - LS-F12801 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 0.156 Range 1.371-333.3 pg/ml

Human Fas Ligand ELISA Kit - RAB0178 from Sigma-Aldrich Category ELISA Kit Prices $423.50 Sizes 1 kt

Human Fas Ligand/TNFSF6 Quantikine ELISA Kit - DFL00 from R&D Systems Category ELISA Kit Prices $479.00 Sizes 1 kit Sensitivity 8.05 pg/mL Range 15.6 - 1,000 pg/mL (Cell Culture Supernates, Cell Lysates, Serum, EDTA Plasma, Heparin Plasma)

Mouse Fas Ligand/TNFSF6 Quantikine ELISA Kit - MFL00 from R&D Systems Category ELISA Kit Prices $479.00 Sizes 1 kit Sensitivity 3.9 pg/mL Range 31.2 - 2,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma)

Human Fas Ligand/TNFSF6 DuoSet ELISA - DY126 from R&D Systems Category ELISA Kit Prices $649.00 Sizes 1 kit (for 15 Plates) Range 31.20 - 2,000 pg/mL

Mouse Fas Ligand/TNFSF6 DuoSet ELISA - DY526 from R&D Systems Category ELISA Kit Prices $649.00 Sizes 1 kit (for 15 Plates) Range 15.60 - 1,000 pg/mL

Quantikine Immunoassay Control Set 402 for Human Fas Ligand - QC89 from R&D Systems Category ELISA Kit Prices $125.00 Sizes 1 each

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