FASLG

Gene Symbol	FASLG
Entrez Gene	356
Alt Symbol	ALPS1B, APT1LG1, APTL, CD178, CD95-L, CD95L, FASL, TNFSF6
Species	Human
Gene Type	protein-coding
Description	Fas ligand (TNF superfamily, member 6)
Other Description	CD95 ligand|apoptosis (APO-1) antigen ligand 1|apoptosis antigen ligand|fas antigen ligand|tumor necrosis factor ligand superfamily member 6
Swissprots	Q9BZP9 P48023
Accessions	AAB96632 AAC39768 ABK41922 BAA32542 CAX86839 CBX53895 CCA94585 EAW90935 EAW90936 P48023 AF288573 AAG60017 AK314874 BAG37389 AY225406 AAO43991 AY858799 AAX49569 BC017502 AAH17502 D38122 BAA07320 DA916336 DQ893466 ABM84392 DQ896147 ABM87146 U08137 AAC50071 U11821 AAC50124 X89102 CAA61474 NM_000639 NP_000630 NM_001302746 NP_001289675
Function	Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. May be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. Binding to the decoy receptor TNFRSF6B/DcR3 modulates its effects. {ECO:0000269|PubMed:17557115}.
Subcellular Location	FasL intracellular domain: Nucleus. Note=The FasL ICD cytoplasmic form is translocated into the nucleus.
Top Pathways	PI3K-Akt signaling pathway, Herpes simplex infection, Chagas disease (American trypanosomiasis), Non-alcoholic fatty liver disease (NAFLD), Proteoglycans in cancer

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human Fas Ligand full length protein - ab157085 from Abcam Category Protein Prices $302.00 Sizes 10 µg Source HEK 293 cells Species Human

Active human Fas Ligand protein fragment - ab168908 from Abcam Category Protein Prices $588.00 Sizes 50 µg Source HEK 293 cells Species Human

Active human Fas Ligand protein fragment - ab186673 from Abcam Category Protein Prices $110.00, $308.00 Sizes 2 µg, 10 µg Source CHO Species Human

Fas Ligand peptide - ab2441 from Abcam Category Peptide

Human Fas Ligand full length protein - ab131850 from Abcam Category Protein Source Wheat germ Species Human

Human Fas Ligand full length protein - ab139255 from Abcam Category Protein Source E. coli Species Human

Human Fas Ligand protein fragment - ab109359 from Abcam Category Protein Source HEK 293 cells Species Human

FASLG / Fas Ligand Antibody Blocking Peptide - LS-E10662 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Fas Ligand/TNFSF6 Protein - NBP2-35264 from Novus Biologicals Category Protein Prices $69.00, $169.00, $3,469.00 Sizes 5 µg, 20 µg, 1 mg Source E. coli Species Human

Fas Ligand/TNFSF6 Partial Recombinant Protein - H00000356-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Fas Ligand/TNFSF6 Recombinant Protein - H00000356-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human Fas Ligand/TNFSF6 Protein - NBP2-23039 from Novus Biologicals Category Protein Prices $269.00 Sizes 100 µg Species Human

Fas Ligand/TNFSF6 Recombinant Protein - H00000356-G01 from Novus Biologicals Category Protein Prices $579.00 Sizes 10 µg Species Human

Fas Ligand Recombinant Protein (Active) - GTX48225-PRO from GeneTex Category Protein Prices $299.00 Sizes 10 μg Source Hamster Species Human

Recombinant Human Fas Ligand/TNFSF6 - 126-FL-010 from R&D Systems Category Protein Source Chinese Hamster Ovary cell line, CHO-derived, Pro134-Leu281, with an N-terminal Met and 6-His tag

Recombinant Human Fas Ligand/TNFSF6, CF - 126-FL-010/CF from R&D Systems Category Protein Source Chinese Hamster Ovary cell line, CHO-derived, Pro134-Leu281, with an N-terminal Met and 6-His tag

Recombinant Mouse Fas Ligand/TNFSF6 - 526-SA-050 from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived, Pro132-Leu279, with an N-terminal Met and 6-His tag

Recombinant Mouse Fas Ligand/TNFSF6, CF - 526-SA-050/CF from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived, Pro132-Leu279, with an N-terminal Met and 6-His tag

Human FASLG protein - orb244199 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

Human FASLG protein - orb244198 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

Human CD95L protein (His Tag) - orb138500 from Biorbyt Category Protein Prices $434.00, $646.00 Sizes 10 μg, 20 μg Source Yeast Species Human

Human FASLG protein - orb245832 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

FasL protein - 30R-AF033 from Fitzgerald Category Protein Prices $225.00 Sizes 10 µg Source CHO cells

FASLG Blocking Peptide - 33R-6103 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

FASLG protein (His tag) - 30R-2954 from Fitzgerald Category Protein Prices $270.00 Sizes 100 µg Source E.coli

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