FASLG

Gene Symbol FASLG
Entrez Gene 356
Alt Symbol ALPS1B, APT1LG1, APTL, CD178, CD95-L, CD95L, FASL, TNFSF6
Species Human
Gene Type protein-coding
Description Fas ligand (TNF superfamily, member 6)
Other Description CD95 ligand|apoptosis (APO-1) antigen ligand 1|apoptosis antigen ligand|fas antigen ligand|tumor necrosis factor ligand superfamily member 6
Swissprots Q9BZP9 P48023
Accessions AAB96632 AAC39768 ABK41922 BAA32542 CAX86839 CBX53895 CCA94585 EAW90935 EAW90936 P48023 AF288573 AAG60017 AK314874 BAG37389 AY225406 AAO43991 AY858799 AAX49569 BC017502 AAH17502 D38122 BAA07320 DA916336 DQ893466 ABM84392 DQ896147 ABM87146 U08137 AAC50071 U11821 AAC50124 X89102 CAA61474 NM_000639 NP_000630 NM_001302746 NP_001289675
Function Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. May be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. Binding to the decoy receptor TNFRSF6B/DcR3 modulates its effects. {ECO:0000269|PubMed:17557115}.
Subcellular Location FasL intracellular domain: Nucleus. Note=The FasL ICD cytoplasmic form is translocated into the nucleus.
Top Pathways PI3K-Akt signaling pathway, Herpes simplex infection, Chagas disease (American trypanosomiasis), Non-alcoholic fatty liver disease (NAFLD), Proteoglycans in cancer

FASLG-Over-expression-Lysate - LY10448a from Abgent, a WuXi AppTec company

Category Cell Lysate
Prices $325.00
Sizes 100 µg
Western blot analysis of his-tag FASLG (arrow) using his tag antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the FASLG gene (Lane 2, Cat. #LY10448a).

CD178 / FAS Ligand Lysate(Denatured) - H00000356-T01 from Acris Antibodies

Category Cell Lysate
Prices $320.00
Sizes 100 µl

FASLG 293 Cell Lysate - 400280 from ABBIOTEC

Category Cell Lysate
Prices $392.00
Sizes 100 µg

Fas Ligand/TNFSF6 Overexpression Lysate (Denatured) - H00000356-T01 from Novus Biologicals

Category Cell Lysate
Prices $279.00
Sizes 100 µl

Fas Ligand/TNFSF6 Overexpression Lysate (Native) - NBL1-10600 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: Fas Ligand Overexpression Lysate (Adult Normal) [NBL1-10600] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Fas Ligand.

FAS-L (h): 293T Lysate - sc-159339 from Santa Cruz Biotechnology

Category Cell Lysate
Prices $205.00
Sizes 100 µg/200 µl
Species Human

FASLG Over-expression Lysate Product - GWB-4C0BEE from Genway Biotech

Category Cell Lysate
Prices $346.00
Sizes 100 µg
Species Human

Panoply™ Human FASLG Knockdown Stable Cell Line - CSC-DC005539 from Creative biogene

Category Cell Line
Species Human
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