| Gene Symbol |
HIST2H2AC
|
| Entrez Gene |
8338
|
| Alt Symbol |
H2A, H2A-GL101, H2A/q, H2AFQ
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
histone cluster 2, H2ac
|
| Other Description |
H2A histone family, member Q|histone 2, H2ac|histone H2A type 2-C|histone H2A-GL101|histone H2A/q|histone IIa
|
| Swissprots |
Q8IUE5 Q6DRA7 Q16777
|
| Accessions |
AAN59959 AAT68255 CAA41050 CAI12569 EAW53604 Q16777 BC060324 AAH60324 EU446979 ABZ92508 NM_003517 NP_003508
|
| Function |
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
|
| Subcellular Location |
Nucleus. Chromosome.
|
| Top Pathways |
Systemic lupus erythematosus, Alcoholism
|
