Gene Symbol | HIST2H2AC |
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Entrez Gene | 8338 |
Alt Symbol | H2A, H2A-GL101, H2A/q, H2AFQ |
Species | Human |
Gene Type | protein-coding |
Description | histone cluster 2, H2ac |
Other Description | H2A histone family, member Q|histone 2, H2ac|histone H2A type 2-C|histone H2A-GL101|histone H2A/q|histone IIa |
Swissprots | Q8IUE5 Q6DRA7 Q16777 |
Accessions | AAN59959 AAT68255 CAA41050 CAI12569 EAW53604 Q16777 BC060324 AAH60324 EU446979 ABZ92508 NM_003517 NP_003508 |
Function | Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. |
Subcellular Location | Nucleus. Chromosome. |
Top Pathways | Systemic lupus erythematosus, Alcoholism |
Histone cluster 2 H2AC CRISPR/Cas9 KO Plasmid (h) - sc-411141 from Santa Cruz Biotechnology
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Histone cluster 2 H2AC HDR Plasmid (h) - sc-411141-HDR from Santa Cruz Biotechnology
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Histone cluster 2 H2AC Double Nickase Plasmid (h) - sc-411141-NIC from Santa Cruz Biotechnology
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Histone cluster 2 H2AC Double Nickase Plasmid (h2) - sc-411141-NIC-2 from Santa Cruz Biotechnology
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Histone cluster 2 H2AC CRISPR Activation Plasmid (h) - sc-411141-ACT from Santa Cruz Biotechnology
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Histone cluster 2 H2AC CRISPR Activation Plasmid (h2) - sc-411141-ACT-2 from Santa Cruz Biotechnology
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Histone cluster 2 H2AC Lentiviral Activation Particles (h) - sc-411141-LAC from Santa Cruz Biotechnology
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Histone cluster 2 H2AC Lentiviral Activation Particles (h2) - sc-411141-LAC-2 from Santa Cruz Biotechnology
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Histone cluster 2 H2AC siRNA (h) - sc-105509 from Santa Cruz Biotechnology
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Histone cluster 2 H2AC shRNA Plasmid (h) - sc-105509-SH from Santa Cruz Biotechnology
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Histone cluster 2 H2AC shRNA (h) Lentiviral Particles - sc-105509-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN10108 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10108 from Sigma-Aldrich
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HIST2H2AC siRNA (Human) - CRH5458 from Cohesion Biosciences
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Histone H2a RNAi - H00008338-R01 from Novus Biologicals
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HIST2H2AC - MBS8239235 from MyBioSource
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shRNA set against Human HIST2H2AC (NM_003517.2) - SHH312897 from Creative biogene
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shRNA set against Human HIST2H2AC(NM_003517.2) - SHH123571 from Creative biogene
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Human HIST2H2AC siRNA - orb265960 from Biorbyt
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HIST2H2AC shRNA Plasmid (Human) - CHH5458 from Cohesion Biosciences
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HIST2H2AC miRNA 3'UTR clone - MiUTR1H-04566 from Creative biogene
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