MAP6

Gene Symbol MAP6
Entrez Gene 4135
Alt Symbol MAP6-N, MTAP6, N-STOP, STOP
Species Human
Gene Type protein-coding
Description microtubule-associated protein 6
Other Description CTD-2530H12.7|MAP-6|stable tubule-only polypeptide
Swissprots Q6P3T0 Q6ZWB8 A7E2A1 Q96JE9
Accessions Q96JE9 AB058781 BAB47507 AK054873 AK096511 AK123340 BAC85586 BC041411 BC063860 AAH63860 BC139780 AAI39781 BC150254 AAI50255 HG503990 XM_006718556 XP_006718619 XM_011545037 XP_011543339 XM_011545038 XP_011543340 XM_011545039 XP_011543341 XR_949931 XR_949932 XR_949933 NM_033063 NP_149052 NM_207577 NP_997460
Function Involved in microtubule stabilization in many cell types, including neuronal cells. Specifically has microtubule cold stabilizing activity. Involved in dendrite morphogenesis and maintenance by regulating lysosomal trafficking via its interaction with TMEM106B. {ECO:0000269|PubMed:24357581}.
Subcellular Location Cytoplasm, cytoskeleton {ECO:0000269|PubMed:14692697}. Golgi apparatus {ECO:0000250}. Note=Colocalizes with neurofilament (NF)-rich inclusions in spinal chord and brain neurons of patients with amyotrophic lateral sclerosis (ALS).
Tissue Specificity Expressed in brain (at protein level). Expressed in spinal chord. Isoform 2 expression is up-regulated in the prefrontal cortex (Brodmann's area 46) of patients with schizophrenia (postmortem brain study). {ECO:0000269|PubMed:14692697, ECO:0000269|PubMed:16624526}.

STOP CRISPR/Cas9 KO Plasmid (h) - sc-407622 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

STOP HDR Plasmid (h) - sc-407622-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

STOP Double Nickase Plasmid (h) - sc-407622-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

STOP Double Nickase Plasmid (h2) - sc-407622-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

STOP CRISPR Activation Plasmid (h) - sc-407622-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

STOP CRISPR Activation Plasmid (h2) - sc-407622-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

STOP Lentiviral Activation Particles (h) - sc-407622-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

STOP Lentiviral Activation Particles (h2) - sc-407622-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

STOP siRNA (h) - sc-63359 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

STOP shRNA Plasmid (h) - sc-63359-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

STOP shRNA (h) Lentiviral Particles - sc-63359-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU037031 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN13003 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND13003 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MAP6 siRNA (Human) - CRH2810 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human MAP6 (NM_033063.1) - SHH337859 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human MAP6(NM_207577.1) - SHH174935 from Creative biogene

Category siRNA
Species Reactivities Human

MAP6 shRNA Plasmid (Human) - CHH2810 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

MAP6 miRNA 3'UTR clone - MiUTR1H-06073 from Creative biogene

Species Reactivities Human

MAP6 miRNA 3'UTR clone - MiUTR1H-06074 from Creative biogene

Species Reactivities Human
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