| Gene Symbol | NPVF |
|---|---|
| Entrez Gene | 64111 |
| Alt Symbol | C7orf9, RFRP |
| Species | Human |
| Gene Type | protein-coding |
| Description | neuropeptide VF precursor |
| Other Description | FMRFamide-related peptide|FMRFamide-related peptides|RFamide-related peptide|neuropeptide NPVF|pro-FMRFamide-related neuropeptide VF |
| Swissprots | Q7LE27 Q96PI9 A4D164 Q9HCQ7 |
| Accessions | AAL90458 AAP22339 EAL24237 EAW93830 Q9HCQ7 AB040290 BAB17674 AF330057 AAK94201 AF440392 AAL90453 BC160068 AAI60068 BM714303 NM_022150 NP_071433 |
| Function | Neuropeptide RFRP-1 acts as a potent negative regulator of gonadotropin synthesis and secretion. Neuropeptides NPSF and NPVF efficiently inhibit forskolin-induced production of cAMP, but RFRP-2 shows no inhibitory activity. Neuropeptide RFRP-1 induces secretion of prolactin in rats. Neuropeptide NPVF blocks morphine- induced analgesia. {ECO:0000269|PubMed:11025660, ECO:0000269|PubMed:20027225}. |
| Subcellular Location | Secreted. |
| Tissue Specificity | Isoform 1 is specifically expressed in the retina. Neuropeptides RFRP-1 and NPVF are detected in the hypothalamus. {ECO:0000269|PubMed:11951088, ECO:0000269|PubMed:20027225}. |
NPVF - SP2460b from Abgent, a WuXi AppTec company
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NPVF - SP2460a from Abgent, a WuXi AppTec company
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NPSF-1-37-Neuropeptide-SF-1-37 - SP2414b from Abgent, a WuXi AppTec company
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NPSF-1-37-Neuropeptide-SF-1-37 - SP2414a from Abgent, a WuXi AppTec company
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RFRP-1 Peptide - 350361 from ABBIOTEC
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RF-NH2 Peptide - 350360 from ABBIOTEC
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RFRP-1 Human - GWB-C57597 from Genway Biotech
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Recombinant Human FMRFamide-related peptides(NPVF) - CSB-YP881030HU CSB-EP881030HU CSB-BP881030HU CSB-MP881030HU from Cusabio
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RFRP-3 Peptide - 350591 from ABBIOTEC
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NPVF Recombinant Protein Antigen - NBP1-86724PEP from Novus Biologicals
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NPVF - A25020 from Creative Peptides
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NPVF Peptide, Human - M34GP10575H from Creative Peptides
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NPVF - AS-62006 from AnaSpec, Inc.
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