SPDYC

Gene Symbol	SPDYC
Entrez Gene	387778
Alt Symbol	RINGOC, Ringo2
Species	Human
Gene Type	protein-coding
Description	speedy/RINGO cell cycle regulator family member C
Other Description	RINGO C|hSpy/Ringo C|rapid inducer of G2/M progression in oocytes C|speedy C|speedy homolog C|speedy protein C
Swissprots	B2RP32 B7ZMH7 Q5MJ68
Accessions	EAW74363 Q5MJ68 AY820305 AAW30396 BC137244 AAI37245 BC137246 AAI37247 BC144548 AAI44549 XM_011545020 XP_011543322 NM_001008778 NP_001008778
Function	Promotes progression through the cell cycle via binding and activation of CDK1 and CDK2. Involved in the spindle-assembly checkpoint. Required for recruitment of MAD2L1, BUBR1 and BUB1 to kinetochores. Required for the correct localization of the active form of Aurora B in prometaphase. {ECO:0000269|PubMed:15611625, ECO:0000269|PubMed:20605920}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:20605920}. Note=Colocalizes with tubulin gamma during interphase. During mitosis, enriched at the spindle poles and the midbody during telophase.
Tissue Specificity	Expressed in a variety of tissues including bone marrow, kidney, small intestine, liver, placenta and testis. {ECO:0000269|PubMed:15611625}.
Top Pathways	Progesterone-mediated oocyte maturation, Oocyte meiosis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Speedy protein C full length protein - ab166404 from Abcam Category Protein Source Wheat germ Species Human

Recombinant Human SPDYC Protein - H00387778-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Source Wheat Germ Species Human

SPDYC-Antibody-N-term-Blocking-Peptide - BP16461a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Speedy C / RINGO C - H00387778-P01 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Species Human

SPDYC fusion protein - ag18754 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

SPDYC fusion protein - ag18126 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human Speedy protein C(SPDYC) - CSB-YP702803HU CSB-EP702803HU CSB-BP702803HU CSB-MP702803HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

SPDYC Recombinant Protein Antigen - NBP1-80832PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

SPDYC Peptide, Human - M34GP15021H from Creative Peptides Category Peptide Source Synthetic. Species Human

Speedy protein C (SPDYC), Recombinant Protein - MBS1472534 from MyBioSource Category Protein Prices $1,050.00, $1,050.00, $1,280.00, $1,280.00, $1,630.00, $1,630.00, $2,095.00, $2,095.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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