HELB
| Gene Symbol | HELB |
|---|---|
| Entrez Gene | 92797 |
| Alt Symbol | hDHB |
| Species | Human |
| Gene Type | protein-coding |
| Description | helicase (DNA) B |
| Other Description | DNA helicase B |
| Swissprots | A8K4C9 Q4G0T2 Q9H7L5 Q8NG08 |
| Accessions | EAW97165 EAW97166 EAW97167 Q8NG08 AA070301 AF319995 AAM73554 AK290894 BAF83583 BC037946 BC143409 BC143411 BC148592 AAI48593 BC157019 AAI57020 DN997712 XM_005269234 XP_005269291 XR_245966 NM_033647 NP_387467 |
| Function | Unwinds duplex DNA with 5'-3' polarity. Has single- strand DNA-dependent ATPase and DNA helicase activities. Prefers ATP and dATP as substrates. During S phase, may facilitate cellular recovery from replication stress. {ECO:0000269|PubMed:12181327, ECO:0000269|PubMed:22194613}. |
| Subcellular Location | Note=Preferentially during S phase, recruited to chromatin following DNA damage induced by UV irradiation, or camptothecin or hydroxyurea treatment. |
| Tissue Specificity | Highly expressed in testis and thymus and weakly in liver, spleen, kidney and brain. {ECO:0000269|PubMed:12181327}. |
HELB Antibody Blocking Peptide - LS-E13081 from LifeSpan Bioscience
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HELB fusion protein - Ag20335 from Proteintech Group
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HELB fusion protein - ag20345 from Proteintech Group
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Recombinant Human HELB, GST-tagged - HELB-13729H from Creative Biomart
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Recombinant Human HELB - HELB-1234H from Creative Biomart
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Recombinant Human DNA helicase B(HELB) ,partial - CSB-YP836741HU CSB-EP836741HU CSB-BP836741HU CSB-MP836741HU from Cusabio
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DNA helicase B / HELB - TP317186 from Acris Antibodies
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HELB Peptide, Human - M34GP06927H from Creative Peptides
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DNA helicase B (HELB), partial, Recombinant Protein - MBS1364588 from MyBioSource
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