HELB

Gene Symbol HELB
Entrez Gene 92797
Alt Symbol hDHB
Species Human
Gene Type protein-coding
Description helicase (DNA) B
Other Description DNA helicase B
Swissprots A8K4C9 Q4G0T2 Q9H7L5 Q8NG08
Accessions EAW97165 EAW97166 EAW97167 Q8NG08 AA070301 AF319995 AAM73554 AK290894 BAF83583 BC037946 BC143409 BC143411 BC148592 AAI48593 BC157019 AAI57020 DN997712 XM_005269234 XP_005269291 XR_245966 NM_033647 NP_387467
Function Unwinds duplex DNA with 5'-3' polarity. Has single- strand DNA-dependent ATPase and DNA helicase activities. Prefers ATP and dATP as substrates. During S phase, may facilitate cellular recovery from replication stress. {ECO:0000269|PubMed:12181327, ECO:0000269|PubMed:22194613}.
Subcellular Location Note=Preferentially during S phase, recruited to chromatin following DNA damage induced by UV irradiation, or camptothecin or hydroxyurea treatment.
Tissue Specificity Highly expressed in testis and thymus and weakly in liver, spleen, kidney and brain. {ECO:0000269|PubMed:12181327}.

HELB CRISPR/Cas9 KO Plasmid (h) - sc-410238 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

HELB HDR Plasmid (h) - sc-410238-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HELB Double Nickase Plasmid (h) - sc-410238-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HELB Double Nickase Plasmid (h2) - sc-410238-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HELB CRISPR Activation Plasmid (h) - sc-410238-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

HELB CRISPR Activation Plasmid (h2) - sc-410238-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

HELB Lentiviral Activation Particles (h) - sc-410238-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HELB Lentiviral Activation Particles (h2) - sc-410238-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HELB siRNA (h) - sc-95729 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

HELB shRNA Plasmid (h) - sc-95729-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

HELB shRNA (h) Lentiviral Particles - sc-95729-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN9966 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9966 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

HELB siRNA (Human) - CRJ4166 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

HELB - MBS8203696 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human Helb (NM_033647.3) - SHH311429 from Creative biogene

Category siRNA
Species Reactivities Human

Human HELB siRNA - orb274667 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

HELB shRNA Plasmid (Human) - CHJ4166 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

HELB miRNA 3'UTR clone - MiUTR3H-13292 from Creative biogene

Species Reactivities Human
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