DBF4

Gene Symbol	DBF4
Entrez Gene	10926
Alt Symbol	ASK, CHIF, DBF4A, ZDBF1
Species	Human
Gene Type	protein-coding
Description	DBF4 zinc finger
Other Description	DBF4 homolog|DBF4 zinc finger A|DBF4-type zinc finger-containing protein 1|activator of S phase kinase|chiffon homolog A|protein DBF4 homolog A|zinc finger, DBF-type containing 1
Swissprots	A8K954 Q75N01 Q9UBU7 Q75MS6 A4D1D8 Q9Y2M6 O75226
Accessions	AAS07418 AAS07442 EAL24170 EAW76930 EAW76931 EAW76932 Q9UBU7 AB028069 BAA78326 AB028070 BAA78327 AF160249 AAD41911 AF160876 AAD45357 AK022969 BAG51144 AK292569 BAF85258 AK302010 BAG63412 AK303175 BAH13912 BC014909 BC022811 BC035632 BC036045 AAH36045 BC047693 AAH47693 XM_005250120 XP_005250177 XM_005250121 XP_005250178 XM_005250122 XP_005250179 XM_006715843 XP_006715906 XM_011515764 XP_011514066 XM_011515765 XP_011514067 XR_927343 NM_006716 NP_006707
Function	Regulatory subunit for CDC7 which activates its kinase activity thereby playing a central role in DNA replication and cell proliferation. Required for progression of S phase. The complex CDC7-DBF4A selectively phosphorylates MCM2 subunit at 'Ser-40' and 'Ser-53' and then is involved in regulating the initiation of DNA replication during cell cycle. {ECO:0000269|PubMed:10373557, ECO:0000269|PubMed:10523313, ECO:0000269|PubMed:17062569}.
Subcellular Location	Nucleus {ECO:0000269|PubMed:10373557}.
Tissue Specificity	Highly expressed in testis and thymus. Expressed also in most cancer cells lines. {ECO:0000269|PubMed:10373557}.
Top Pathways	Cell cycle

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human DBF4 full length protein - ab161204 from Abcam Category Protein Source Wheat germ Species Human

Human DBF4 full length protein - ab161205 from Abcam Category Protein Source Wheat germ Species Human

Human DBF4 protein fragment - ab161206 from Abcam Category Protein Source Wheat germ Species Human

DBF4 Antibody Blocking Peptide - LS-E27687 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

DBF4 Antibody Blocking Peptide - LS-E18772 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human DBF4 Protein - H00010926-P02 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Source Wheat Germ Species Human

Recombinant Human DBF4 Protein - H00010926-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Source Wheat Germ Species Human

Recombinant Human DBF4 Protein - H00010926-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Dbf4 Immunizing peptide - orb66220 from Biorbyt Category Peptide Prices $247.00 Sizes 100 μg Species Human, Mouse, Rat

DBF4 peptide - orb218382 from Biorbyt Category Peptide Prices $272.00, $510.00 Sizes 1 mg, 5 mg Species Human

DBF4 Blocking Peptide - abx063713 from Abbexa Category Peptide Species Human, Bovine, Pig

DBF4 / ASK - H00010926-P01 from Acris Antibodies Category Protein Prices $340.00 Sizes 2 µg Species Human

DBF4 / ASK - H00010926-P02 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Species Human

DBF4 / ASK - H00010926-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

DBF4 / ASK - H00010926-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

DBF4 fusion protein - ag3771 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human DBF4 - DBF4-689H from Creative Biomart Category Protein Source Mammalian Cells Species Human

DBF4 Blocking Peptide - CBP2519 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Bovine, Pig

Dbf4 (I18) Peptide - BS2372P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Recombinant Human Protein DBF4 homolog A(DBF4) - CSB-YP887010HU CSB-EP887010HU CSB-BP887010HU CSB-MP887010HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

ASK-Antibody-N-term-Blocking-Peptide - BP7289a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

ASK-Blocking-Peptide-C-term - BP7289b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

DBF4 Peptide, Human - M34GP04041H from Creative Peptides Category Peptide Source Synthetic. Species Human

DBF4 Recombinant Protein Antigen - NBP2-55268PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

Protein DBF4 homolog A (DBF4), Recombinant Protein - MBS1411739 from MyBioSource Category Protein Prices $1,475.00, $1,475.00, $1,705.00, $1,705.00, $2,515.00, $2,515.00, $2,960.00, $2,960.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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