| Gene Symbol |
DSG2
|
| Entrez Gene |
1829
|
| Alt Symbol |
ARVC10, ARVD10, CDHF5, CMD1BB, HDGC
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
desmoglein 2
|
| Other Description |
HDGC|cadherin family member 5|desmoglein-2
|
| Swissprots |
Q14126 Q4KKU6
|
| Accessions |
CAC81989 EAX01261 EAX01262 Q14126 AK308408 BC014581 BC014584 BC017410 BC022413 BC065747 BC067229 BC071764 BC099655 AAH99655 BC099656 AAH99656 BC099657 AAH99657 BP353513 CN347023 CN395083 DC417739 DR158777 Z26317 CAA81226 NM_001943 NP_001934
|
| Function |
Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
|
| Subcellular Location |
Cell membrane; Single-pass type I membrane protein. Cell junction, desmosome.
|
| Tissue Specificity |
All of the tissues tested and carcinomas.
|
| Top Pathways |
Arrhythmogenic right ventricular cardiomyopathy (ARVC)
|