DSG2

Gene Symbol DSG2
Entrez Gene 1829
Alt Symbol ARVC10, ARVD10, CDHF5, CMD1BB, HDGC
Species Human
Gene Type protein-coding
Description desmoglein 2
Other Description HDGC|cadherin family member 5|desmoglein-2
Swissprots Q14126 Q4KKU6
Accessions CAC81989 EAX01261 EAX01262 Q14126 AK308408 BC014581 BC014584 BC017410 BC022413 BC065747 BC067229 BC071764 BC099655 AAH99655 BC099656 AAH99656 BC099657 AAH99657 BP353513 CN347023 CN395083 DC417739 DR158777 Z26317 CAA81226 NM_001943 NP_001934
Function Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
Subcellular Location Cell membrane; Single-pass type I membrane protein. Cell junction, desmosome.
Tissue Specificity All of the tissues tested and carcinomas.
Top Pathways Arrhythmogenic right ventricular cardiomyopathy (ARVC)

DSG2 (10D2) Mouse mAb (IF Specific) - 12631 from Cell Signaling Technology

Prices $239.00
Sizes 100 µl (100 tests)
Host Mouse
Clonality Monoclonal
Clone 10D2
Confocal immunofluorescent analysis of unpermeabilized A-431 cells using DSG2 (10D2) Mouse mAb (IF Specific) (green). Blue pseudocolor = DRAQ5® #4084 (fluorescent DNA dye).

dsg2 (F-8) - sc-365856 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
dsg2 (F-8): sc-365856. Western blot analysis of dsg2 expression in ECV304 whole cell lysate.

dsg2 (F-5) - sc-390531 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
dsg2 (F-5): sc-390531. Western blot analysis of dsg2 expression in HeLa whole cell lysate.

dsg2 (AH12.2) - sc-80663 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
dsg2 (AH12.2): sc-80663. Immunofluorescence staining of methanol-fixed HeLa cells showing membrane localization.

dsg2 (8E5) - sc-23911 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
dsg2 (8E5): sc-23911. Immunofluorescence staining of methanol-fixed SCC-4 cells showing membrane localization.

dsg2 (H-145) - sc-20115 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
dsg2 (H-145): sc-20115. Immunoperoxidase staining of formalin-fixed, paraffin-embedded human breast tumor showing membrane staining.

dsg2 (T-20) - sc-14859 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

dsg2 (V-19) - sc-14860 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
dsg2 (V-19): sc-14860. Immunofluorescence staining of methanol-fixed HeLa cells showing membrane localization.

dsg2 (13B11) - sc-135815 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal

dsg2 (6D8) - sc-53486 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
dsg2 (6D8): sc-53486. Western blot analysis of dsg2 expression in ECV304 (A), T24 (B), SCC-4 (C), SW480 (D), A549 (E), JEG-3 (F) and A-431 (G) whole cell lysates.

Anti-Desmoglein 2 antibody - ab85632 from Abcam

Prices $379.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-Desmoglein 2 antibody (ab85632) at 1 µg/ml (in 5% skim milk / PBS buffer) + Hela cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-Desmoglein 2 antibody - ab96761 from Abcam

Prices $376.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Desmoglein 2 antibody (ab96761) at 1/1000 dilutionLane 1 : 293T whole cell lysateLane 2 : H1299 whole cell lysateLane 3 : MOLT4 whole cell lysateLysates/proteins at 30 µg per lane.

Anti-Desmoglein 2 antibody - ab126800 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-Desmoglein 2 antibody - ab199390 from Abcam

Prices $359.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Desmoglein 2 antibody (ab199390) at 1/500 dilutionLane 1 : HeLa cell lysateLane 2 : 293T cell lysateLane 3 : A431 cell lysate

Anti-Desmoglein 2 antibody - ab140391 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-Desmoglein 2 antibody (ab140391) at 1 µg/ml + Mouse testis lysate at 10 µg

Anti-Desmoglein 2 antibody [10D2] - ab151445 from Abcam

Prices $378.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 10D2
Anti-Desmoglein 2 antibody [10D2] (ab151445) at 1/100 dilution + HaCat Human keratinocyte cells

Anti-Desmoglein 2 antibody [3G132] - ab14415 from Abcam

Prices $392.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 3G132
ab14415 at a 1/10 dilution staining human urothelium (bladder cancer) by Immunohistochemistry (Formalin-fixed paraffin-embedded sections). The antibody was incubated with the tissue for 30 minutes following heat mediated antigen retrieval and paraformaldehyde fixation. See Abreview

Anti-Desmoglein 2 antibody [EPR6767(B)] - ab124683 from Abcam

Prices $385.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR6767(B)
All lanes : Anti-Desmoglein 2 antibody [EPR6767(B)] (ab124683) at 1/50000 dilutionLane 1 : SKBR3 cell lysateLane 2 : HepG2 cell lysateLane 3 : 293T cell lysateLane 4 : A431 cell lysateLane 5 : HeLa cell lysateLane 6 : T47D cell lysateLysates/proteins at 10 µg per lane.SecondaryGoat anti-Rabbit HRP at 1/2000 dilution

Anti-Desmoglein 2 antibody [EPR6768] - ab150372 from Abcam

Prices $385.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR6768
Overlay histogram showing HeLa cells stained with ab150372 (red line). The cells were fixed with 80% methanol (5 min) and then permeabilized with 0.1% PBS-Tween for 20 min. The cells were then incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific protein-protein interactions followed by the antibody (ab150372, 1/1000 dilution) for 30 min at 22°C. The secondary antibody used was Alexa Fluor® 488 goat anti-rabbit IgG (H&L) (ab150077) at 1/2000 dilution for 30 min at 22°C. Isotype control antibody (black line) was rabbit IgG (monoclonal) (0.1μg/1x106 cells) used under the same conditions. Unlabelled sample (blue line) was also used as a control. Acquisition of >5,000 events were collected using a 20mW Argon ion laser (488nm) and 525/30 bandpass filter. This antibody gave a positive signal in HeLa cells fixed with 4% paraformaldehyde (10 min)/permeabilized with 0.1% PBS-Tween for 20 min used under the same conditions.

Anti-Desmoglein 2 antibody - N-terminal - ab76668 from Abcam

Prices $304.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-Desmoglein 2 antibody - N-terminal (ab76668) at 1/50 dilution + T47D cell lysate at 35 µg

Anti-DSG2 / Desmoglein 2 Antibody - LS-C22812 from LifeSpan Bioscience

Prices $495.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-DSG2 / Desmoglein 2 Antibody - LS-C22813 from LifeSpan Bioscience

Prices $575.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal

Anti-DSG2 / Desmoglein 2 Antibody - LS-C22814 from LifeSpan Bioscience

Prices $620.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-DSG2 / Desmoglein 2 Antibody - LS-C22815 from LifeSpan Bioscience

Prices $620.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-DSG2 / Desmoglein 2 Antibody - LS-C44527 from LifeSpan Bioscience

Prices $595.00
Sizes 200 µg
Host Mouse
Clonality Monoclonal
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