RANGAP1

Gene Symbol RANGAP1
Entrez Gene 5905
Alt Symbol Fug1, RANGAP, SD
Species Human
Gene Type protein-coding
Description Ran GTPase activating protein 1
Other Description ran GTPase-activating protein 1|segregation distorter homolog|segregation distortion
Swissprots P46060 Q96JJ2
Accessions EAW60420 EAW60421 EAW60422 EAW60423 EAW60424 P46060 AB058738 BAB47464 AK302222 BAG63578 AK303524 BAG64552 BC004990 AAH04990 BC014044 AAH14044 BC019676 AAH19676 BC041396 AAH41396 BC048990 BM551472 CR456557 CAG30443 CU013157 CAK54588 CU013445 CAK54887 CX872993 DA269460 HY062550 HY251691 X82260 CAA57714 XM_005261695 XP_005261752 XM_005261696 XP_005261753 XM_006724289 XP_006724352 XM_011530293 XP_011528595 XM_011530294 XP_011528596 XM_011530295 XP_011528597 XM_011530296 XP_011528598 XM_011530297 XP_011528599 NM_001278651 NP_001265580 NM_002883 NP_002874
Function GTPase activator for the nuclear Ras-related regulatory protein Ran, converting it to the putatively inactive GDP-bound state.
Subcellular Location Cytoplasm. Nucleus membrane; Peripheral membrane protein; Cytoplasmic side. Chromosome, centromere, kinetochore {ECO:0000250}. Cytoplasm, cytoskeleton, spindle pole {ECO:0000250}. Note=Cytoplasmic during interphase. Targeted to the nuclear rim after sumoylation. During mitosis, associates with mitotic spindles. Association with kinetochores appears soon after nuclear envelope breakdown and persists until late anaphase. Mitotic location also requires sumoylation.
Tissue Specificity Highly expressed in brain, thymus and testis. {ECO:0000269|PubMed:8973340}.
Top Pathways RNA transport

Human RanGAP1 full length protein - ab131750 from Abcam

Category Protein
Source Wheat germ
Species Human
12.5% SDS-PAGE analysis of ab131750, stained with Coomassie Blue.

Human RanGAP1 peptide - ab22867 from Abcam

Category Peptide
Species Human

RANGAP1 Antibody Blocking Peptide - LS-E2697 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

RANGAP1 Antibody Blocking Peptide - LS-E25671 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

RANGAP1 Antibody Blocking Peptide - LS-E20527 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

RANGAP1 Antibody Blocking Peptide - LS-E20528 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Recombinant Human RanGAP1 Protein - H00005905-P01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

RANGAP1-Antibody-N-term-Blocking-peptide - BP13776a from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

RANGAP1 blocking peptide - GTX22081-PEP from GeneTex

Category Peptide
Prices $239.00
Sizes 100 μg
Species Human, Mouse, Dog, Rat, Bovine

RanGAP1 Blocking Peptide - 33R-5742 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

RANGAP1 Peptide - AC21-0501-P from Abcore

Category Peptide
Prices $160.00
Sizes 100 µg

RanGAP1 - H00005905-P01-02 from Acris Antibodies

Category Protein
Prices $300.00
Sizes 2 µg
Source in vitro transl.
Species Human

RANGAP1 Peptide - 45-135P from ProSci

Category Peptide
Prices $175.00
Sizes 100 µg
Species Human, Mouse

RANGAP1 fusion protein - ag1563 from Proteintech Group

Category Protein
Source E. coli-derived, PGEX-4T
Species Human

Recombinant Human Ran GTPase Activating Protein 1, GST-tagged - RANGAP1-682H from Creative Biomart

Category Protein
Source E. coli.

Recombinant Human RANGAP1, His-tagged - RANGAP1-30474TH from Creative Biomart

Category Protein
Source E. coli
Species Human

Recombinant Human Ran GTPase-activating protein 1(RANGAP1) - CSB-YP019318HU CSB-EP019318HU CSB-BP019318HU CSB-MP019318HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

RanGAP1 - TP304223 from Acris Antibodies

Category Protein
Prices $680.00
Sizes 20 µg
Source HEK293 cells
Species Human
RanGAP1

RanGAP 1, Peptide - MBS658425 from MyBioSource

Category Peptide
Prices $340.00
Sizes 100 µg
Species Mouse, Human

RANGAP1, Peptide - MBS426733 from MyBioSource

Category Peptide
Prices $175.00
Sizes 100 µg
Species Human, Mouse, Rat, Dog, Bovine

RanGAP1 Recombinant Protein Antigen - NBP2-33591PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human

RanGAP1-Ran-GTPase-Antibody-Sumoylation-Site-Specific-Blocking-peptide - BP2503a from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

RANGAP1 Peptide, Human - M34GP12957H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

RANGAP1 fusion protein - Ag26136 from Proteintech Group

Category Protein
Source E. coli -derived, PET28a
Species Human

RanGAP1 Recombinant Protein (Human) (OPED00124) - OPED00124 from Aviva Systems Biology

Category Protein
Prices $245.00
Sizes 100 µg
Source E. Coli
Species Human
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