RANGAP1

Gene Symbol RANGAP1
Entrez Gene 5905
Alt Symbol Fug1, RANGAP, SD
Species Human
Gene Type protein-coding
Description Ran GTPase activating protein 1
Other Description ran GTPase-activating protein 1|segregation distorter homolog|segregation distortion
Swissprots P46060 Q96JJ2
Accessions EAW60420 EAW60421 EAW60422 EAW60423 EAW60424 P46060 AB058738 BAB47464 AK302222 BAG63578 AK303524 BAG64552 BC004990 AAH04990 BC014044 AAH14044 BC019676 AAH19676 BC041396 AAH41396 BC048990 BM551472 CR456557 CAG30443 CU013157 CAK54588 CU013445 CAK54887 CX872993 DA269460 HY062550 HY251691 X82260 CAA57714 XM_005261695 XP_005261752 XM_005261696 XP_005261753 XM_006724289 XP_006724352 XM_011530293 XP_011528595 XM_011530294 XP_011528596 XM_011530295 XP_011528597 XM_011530296 XP_011528598 XM_011530297 XP_011528599 NM_001278651 NP_001265580 NM_002883 NP_002874
Function GTPase activator for the nuclear Ras-related regulatory protein Ran, converting it to the putatively inactive GDP-bound state.
Subcellular Location Cytoplasm. Nucleus membrane; Peripheral membrane protein; Cytoplasmic side. Chromosome, centromere, kinetochore {ECO:0000250}. Cytoplasm, cytoskeleton, spindle pole {ECO:0000250}. Note=Cytoplasmic during interphase. Targeted to the nuclear rim after sumoylation. During mitosis, associates with mitotic spindles. Association with kinetochores appears soon after nuclear envelope breakdown and persists until late anaphase. Mitotic location also requires sumoylation.
Tissue Specificity Highly expressed in brain, thymus and testis. {ECO:0000269|PubMed:8973340}.
Top Pathways RNA transport

RanGAP1 Antibody - 14675 from Cell Signaling Technology

Prices $239.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from various cell lines using RanGAP1 Antibody.

Ran GAP1 (C-5) - sc-28322 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Ran GAP1 (C-5): sc-28322. Immunoperoxidase staining of formalin fixed, paraffin-embedded human oral mucosa tissue showing cytoplasmic and nuclear staining of surface epithelial cells. Kindly provided by The Swedish Human Protein Atlas (HPA) program.

Ran GAP1 (H-180) - sc-25630 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Ran GAP1 (H-180): sc-25630. Immunofluorescence staining of methanol-fixed HeLa cells showing nuclear envelope localization.

Ran GAP1 (N-19) - sc-1862 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Ran GAP1 (N-19): sc-1862. Immunofluorescence staining of methanol-fixed HeLa cells showing nuclear envelope localization.

Anti-RanGAP1 antibody - ab4784 from Abcam

Prices $390.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
ab4784 staining RanGAP1 on skin tissue by Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) 

Anti-RanGAP1 antibody - ab186849 from Abcam

Prices $384.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human lung tissue labelling RanGAP1 with ab186849 at 1/200. Magnification: 400x.

Anti-RanGAP1 antibody - ab88682 from Abcam

Prices $384.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-RanGAP1 antibody (ab88682) at 1 µg/ml + Jurkat cell lysate at 50 µg

Anti-RanGAP1 antibody - ab2081 from Abcam

Prices $376.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
ab2081 at a concentration of 0.2µg/ml staining approximately 70kda RanGAP1 in 3T3 whole cell lysate (RIPA buffer, 35µg total protein per lane) by Western blot (ECL). Primary incubation = 1 hour.

Anti-RanGAP1 antibody - ab105201 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Staining of Human RanGAP1 in a Formalin/PFA-fixed paraffin-embedded section of Human Colon Carcinoma using ab105201 at a dilution of 1/250. Detection utilised DAB staining.

Anti-RanGAP1 antibody [1B4] - ab119092 from Abcam

Prices $384.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1B4
All lanes : Anti-RanGAP1 antibody [1B4] (ab119092) at 1/1000 dilutionLane 1 : HEK293T cell lysate transfected with pCMV6-ENTRY control cDNALane 2 : HEK293T cell lysate transfected with pCMV6-ENTRY RanGAP1 cDNALysates/proteins at 5 µg per lane.developed using the ECL technique

Anti-RanGAP1 antibody [4F9E2] - ab201956 from Abcam

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4F9E2
Anti-RanGAP1 antibody [4F9E2] (ab201956) at 1/500 dilution + Human RANGAP1 (aa359-587) recombinant protein

Anti-RanGAP1 antibody [EPR3295] - ab92360 from Abcam

Prices $99.00, $398.00
Sizes 10 µl, 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR3295
All lanes : Anti-RanGAP1 antibody [EPR3295] (ab92360) at 1/1000 dilutionLane 1 : HeLa cell lysateLane 2 : MCF-7 cell lysateLane 3 : SH-SY5Y cell lysateLane 4 : A549 cell lysateLysates/proteins at 10 µg per lane.SecondaryHRP labelled goat anti-rabbit antibody at 1/2000 dilution

Anti-RanGAP1 antibody - Aminoterminal end - ab59565 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-RanGAP1 antibody - Aminoterminal end (ab59565) at 1/4000 dilutionLane 1 : HEK-293T cells transfected with human RanGAP1Lane 2 : Untransfected HEK-293 cellsLane 3 : HEK-293T cells transfected with human RanGAP1 + Inhibition with RanGAP1 immunizing peptide (human 1-20) (20µg/mL)SecondaryGoat Anti-Rabbit IgG, Peroxidase conjugatedeveloped using the ECL technique

Anti-RanGAP1 antibody - Carboxyterminal end - ab53267 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-RANGAP1 Antibody (N-Terminus) - LS-C9915 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-RANGAP1 Antibody - LS-C334026 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry of paraffin-embedded human lung using RANGAP1 antibody at dilution of 1:200 (400x lens).

Anti-RANGAP1 Antibody (clone 1B4) - LS-C115280 from LifeSpan Bioscience

Prices $350.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1B4
IHC of paraffin-embedded Human liver tissue using anti-RANGAP1 mouse monoclonal antibody. (Dilution 1:50).

Anti-RANGAP1 Antibody (aa20-49, AP) - LS-C267818 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RANGAP1 Antibody (aa20-49, APC) - LS-C267819 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RANGAP1 Antibody (aa20-49, Biotin) - LS-C267820 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RANGAP1 Antibody (aa20-49, FITC) - LS-C267821 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RANGAP1 Antibody (aa20-49, Azide-free, HRP) - LS-C267822 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RANGAP1 Antibody (aa163-212) - LS-C151325 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
RANGAP1 antibody Western Blot of Mouse Heart.

Anti-RANGAP1 Antibody (aa20-49, PE) - LS-C267824 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RANGAP1 Antibody (aa100-150) - LS-C288782 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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