IGF2BP3

Gene Symbol	IGF2BP3
Entrez Gene	10643
Alt Symbol	CT98, IMP-3, IMP3, KOC, KOC1, VICKZ3
Species	Human
Gene Type	protein-coding
Description	insulin-like growth factor 2 mRNA binding protein 3
Other Description	IGF-II mRNA-binding protein 3|IGF2 mRNA-binding protein 3|KH domain containing protein overexpressed in cancer|VICKZ family member 3|cancer/testis antigen 98|insulin-like growth factor 2 mRNA-binding protein 3
Swissprots	Q86VB1 Q6MZZ2 Q63HM0 A0A4Z5 O00425
Accessions	CAP40171 EAL24257 EAW93786 EAW93787 O00425 AF117108 AAD09828 BC019258 BC051296 BC065269 AAH65269 BX640800 CAE45883 BX648488 CAH56186 U76705 AAD09223 U97188 AAC35208 XM_006715639 XP_006715702 XM_011515089 XP_011513391 XM_011515090 XP_011513392 XM_011515091 XP_011513393 XM_011515092 XP_011513394 XM_011515093 XP_011513395 NM_006547 NP_006538
Function	RNA-binding factor that may recruits target transcripts to cytoplasmic protein-RNA complexes (mRNPs). This transcript 'caging' into mRNPs allows mRNA transport and transient storage. It also modulates the rate and location at which target transcripts encounter the translational apparatus and shields them from endonuclease attacks or microRNA-mediated degradation. Binds to the 3'-UTR of CD44 mRNA and stabilizes it, hence promotes cell adhesion and invadopodia formation in cancer cells. Binds to beta- actin/ACTB and MYC transcripts. Binds to the 5'-UTR of the insulin-like growth factor 2 (IGF2) mRNAs. {ECO:0000269|PubMed:16541107, ECO:0000269|PubMed:23640942}.
Subcellular Location	Nucleus. Cytoplasm. Note=Found in lamellipodia of the leading edge, in the perinuclear region, and beneath the plasma membrane. The subcytoplasmic localization is cell specific and regulated by cell contact and growth. Localized at the connecting piece and the tail of the spermatozoa. Colocalized with CD44 mRNA in RNP granules. In response to cellular stress, such as oxidative stress, recruited to stress granules.
Tissue Specificity	Expressed in fetal liver, fetal lung, fetal kidney, fetal thymus, fetal placenta, fetal follicles of ovary and gonocytes of testis, growing oocytes, spermatogonia and semen (at protein level). Expressed in cervix adenocarcinoma, in testicular, pancreatic and renal-cell carcinomas (at protein level). Expressed ubiquitously during fetal development at 8 and 14 weeks of gestation. Expressed in ovary, testis, brain, placenta, pancreatic cancer tissues and pancreatic cancer cell lines. {ECO:0000269|PubMed:10525192, ECO:0000269|PubMed:12161597, ECO:0000269|PubMed:15644775, ECO:0000269|PubMed:16049158, ECO:0000269|PubMed:16814207, ECO:0000269|PubMed:17192788, ECO:0000269|PubMed:9178771, ECO:0000269|PubMed:9891060}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human IMP-3 / IGF2BP3 ELISA Kit (Sandwich ELISA) - LS-F7458 from LifeSpan Bioscience Category ELISA Kit Prices $790.00 Sizes 1 plate Sensitivity 0.156 ng/ml Range 0.156-10 ng/ml

Human IGF2BP3 ELISA Kit - abx151909 from Abbexa Category ELISA Kit Sensitivity 0.055 ng/ml Range 0.156 ng/ml - 10 ng/ml

Insulin Like Growth Factor 2 mRNA Binding Protein 3, IGF2BP3, Human, ELISA Kit - E-EL-H0438 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 0.188 Range 0.313-20ng/mL

Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3), Human, ELISA Kit - CSB-EL011092HU from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Insulin Like Growth Factor 2 mRNA Binding Protein 3, IGF2BP3, Rabbit, ELISA Kit - E-EL-RB0803 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Insulin Like Growth Factor 2 mRNA Binding Protein 3, IGF2BP3, Chicken, ELISA Kit - E-EL-Ch1535 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t

Insulin Like Growth Factor 2 mRNA Binding Protein 3, IGF2BP3, Porcine, ELISA Kit - E-EL-P1090 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Insulin Like Growth Factor 2 mRNA Binding Protein 3, IGF2BP3, Guinea Pig, ELISA Kit - E-EL-GP0815 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t

Insulin Like Growth Factor 2 mRNA Binding Protein 3, IGF2BP3, Monkey, ELISA Kit - E-EL-MK0634 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Human IGF2BP3(Insulin Like Growth Factor 2 mRNA Binding Protein 3) ELISA Kit - E-EL-H0438 from Elabscience Category ELISA Kit Sensitivity 0.19 ng/mL Range 0.31—20 ng/mL

Human IGF2BP3 (Insulin Like Growth Factor 2 mRNA Binding Protein 3) CLIA Kit - E-CL-H0357 from Elabscience Category CLIA Kit Sensitivity 37.50 pg/mL Range Average Recovery (%)

IGF1R3, ELISA Kit - MBS2509192 from MyBioSource Category ELISA Kit Prices $410.00, $490.00, $2,040.00, $3,590.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.188ng/mL Range 0.313--20ng/mL

IGF2BP3, ELISA Kit - MBS2505275 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.188ng/mL Range 0.313-20ng/mL

IGF2BP3, ELISA Kit - MBS2513487 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 37.5pg/mL Range 62.5-4000pg/mL

IGF2BP3, ELISA Kit - MBS2505099 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 75pg/mL Range 125-8000pg/mL

IGF2BP3, ELISA Kit - MBS2505670 from MyBioSource Category ELISA Kit Prices $410.00, $490.00, $2,040.00, $3,590.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of Human IGF2BP3 is 0.188ng/mL (The sensitivity of this assay, or lowest detectable limit (LDL) was defined as the lowest protein concentration that could be differentiated from zero). Range 0.313-20ng/mL

IGF2BP3, ELISA Kit - MBS2511302 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.188ng/mL Range 0.313-20ng/mL

IGF2BP3, ELISA Kit - MBS2511067 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.188ng/mL Range 0.313-20ng/mL

Insulin Like Growth Factor 2 mRNA Binding Protein 3 (IGF2BP3), ELISA Kit - MBS2021974 from MyBioSource Category ELISA Kit Prices $410.00, $610.00, $830.00, $3,420.00, $6,200.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity Typically less than 0.055ng/mL. Range 0.156-10ng/mL

ELISA Kit for Insulin Like Growth Factor 2 mRNA Binding Protein 3 (IGF2BP3) - SEL617Hu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.055ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA’s were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

CLIA Kit for Insulin Like Growth Factor 2 mRNA Binding Protein 3 (IGF2BP3) - SCL617Hu from Uscn Life Science Inc. Category CLIA Kit Sensitivity The minimum detectable dose of this kit is typically less than 9.91pg/mL. Range 27.43-20000pg/mL The standard curve concentrations used for the CLIA’s were 20000pg/mL, 6666.67pg/mL, 2222.22pg/mL, 740.74pg/mL, 246.91pg/mL, 82.3pg/mL, 27.43pg/mL

Human Insulin-like growth factor 2 mRNA-binding protein 3(IGF2BP3) ELISA kit - CSB-EL011092HU from Cusabio Category ELISA Kit Sensitivity 9.37 pg/ml. Range 37.5 pg/ml-2400 pg/ml

Human IGF2BP3(Insulin Like Growth Factor 2 mRNA Binding Protein 3) ELISA Kit - E-EL-H0438 from Iwai North America Inc. Category ELISA Kit Prices $580.00 Sizes 1 kit Sensitivity 0.19 ng/mLng/mL Range 0.31~20 ng/mL

Human GPLD1 (Glycosylphosphatidylinositol Specific Phospholipase D1) CLIA Kit - E-CL-H0323 from Iwai North America Inc. Category CLIA Kit Prices $722.50 Sizes 1 kit Sensitivity 0.469ng/mL Range 0.781-50ng/mL

Insulin Like Growth Factor 2 mRNA Binding Protein 3 (IGF2BP3), Human, ELISA Kit - DL-IGF2BP3-Hu from ARP American Research Products Category ELISA Kit Prices $655.00 Sizes 96 t Range 0.312-20 ng/mL

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