Fermt3

Gene Symbol Fermt3
Entrez Gene 108101
Alt Symbol C79673, Kindlin3
Species Mouse
Gene Type protein-coding
Description fermitin family homolog 3 (Drosophila)
Other Description fermitin family homolog 3|unc-112-related protein 2
Swissprots Q8K1B8
Accessions EDL33286 EDL33287 Q8K1B8 AK090332 AK142912 AK149737 AK158357 AK161025 AK169682 BAE41302 BC025119 AAH25119 BC032204 AAH32204 BC066803 AAH66803 XM_006526593 XP_006526656 XM_006526594 XP_006526657 XM_006526595 XP_006526658 NM_153795 NP_722490
Function Plays a central role in cell adhesion in hematopoietic cells. Acts by activating the integrin beta-1-3 (ITGB1, ITGB2 and ITGB3). Required for integrin-mediated platelet adhesion and leukocyte adhesion to endothelial cells. Required for activation of integrin beta-2 (ITGB2) in polymorphonuclear granulocytes (PMNs). {ECO:0000269|PubMed:18278053, ECO:0000269|PubMed:18662549, ECO:0000269|PubMed:19234461}.
Subcellular Location Cell projection, podosome {ECO:0000269|PubMed:16876785}. Note=Present in the F-actin surrounding ring structure of podosomes, which are specialized adhesion structures of hematopoietic cells.
Tissue Specificity Specifically expressed in hematopoietic cells. {ECO:0000269|PubMed:16876785}.

Mouse FERMT3 ORF clone(NM_153795.2) - CDCG003748 from Creative Biomart

Species Mouse
Accession NM_153795.2

Mouse Fermt3 ORF Clone(NM_153795.2) - CDCL163416 from Creative Biomart

Species Mouse
Accession NM_153795.2

Mouse FERMT3 ORF clone(NM_153795.2) - CDCG003748 from Creative biogene

Species Mouse
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