MINA

Gene Symbol	MINA
Entrez Gene	84864
Alt Symbol	MDIG, MINA53, NO52, ROX
Species	Human
Gene Type	protein-coding
Description	MYC induced nuclear antigen
Other Description	60S ribosomal protein L27a histidine hydroxylase|bifunctional lysine-specific demethylase and histidyl-hydroxylase MINA|histone lysine demethylase MINA|mineral dust induced gene protein|mineral dust-induced gene protein|myc-induced nuclear antigen, 53 kDa|nucleolar protein 52|ribosomal oxygenase MINA
Swissprots	Q8IUF6 Q8IU69 D3DN35 Q6SKS0 Q6AHW4 Q96C17 Q8IUF7 Q96KB0 Q8IUF8
Accessions	EAW79872 EAW79873 EAW79874 EAW79875 Q8IUF8 AB083189 BAC16537 AB083190 BAC16358 AB083191 BAC16359 AB083192 BAC16360 AB083193 BAC16361 AK027299 BAB55024 AL550737 AY302110 AAP59421 AY390536 AAR27293 AY456380 AAR21572 BC014928 AAH14928 BM979079 CR627479 CAH10679 DA310030 DA696177 DQ453796 ABE28016 XM_005247838 XP_005247895 XM_011513244 XP_011511546 XR_241516 NM_001042533 NP_001035998 NM_001261829 NP_001248758 NM_032778 NP_116167 NM_153182 NP_694822
Function	Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. Is involved in the demethylation of trimethylated 'Lys-9' on histone H3 (H3K9me3), leading to an increase in ribosomal RNA expression. Also catalyzes the hydroxylation of 60S ribosomal protein L27a on 'His-39'. May play an important role in cell growth and survival. May be involved in ribosome biogenesis, most likely during the assembly process of pre-ribosomal particles. {ECO:0000269|PubMed:12091391, ECO:0000269|PubMed:14695334, ECO:0000269|PubMed:15534111, ECO:0000269|PubMed:15819408, ECO:0000269|PubMed:15897898, ECO:0000269|PubMed:17317935, ECO:0000269|PubMed:19502796, ECO:0000269|PubMed:23103944}.
Subcellular Location	Nucleus {ECO:0000269|PubMed:12091391, ECO:0000269|PubMed:15819408}. Nucleus, nucleolus {ECO:0000269|PubMed:12091391, ECO:0000269|PubMed:15819408}.
Tissue Specificity	Expressed in liver, skeletal muscle, heart, pancreas, and placenta. Not detected in brain, lung or kidney. Expressed in several lung cancer tissues, but is barely detected in the adjacent non-cancerous tissues. Also highly expressed in several esophageal squamous cell carcinoma (ESCC), and colon cancer tissues, and in various cancer cell lines. {ECO:0000269|PubMed:14695334, ECO:0000269|PubMed:15534111, ECO:0000269|PubMed:15897898, ECO:0000269|PubMed:19502796}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

MINA-Over-expression-Lysate - LY10925a from Abgent, a WuXi AppTec company Category Cell Lysate Prices $325.00 Sizes 100 µg

MINA 293T Cell Transient Overexpression Lysate(Denatured) - H00084864-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

MINA overexpression lysate - LY407126 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

MINA overexpression lysate - LY420967 from Acris Antibodies Category Cell Lysate Prices $480.00 Sizes 100 µg

MINA overexpression lysate - LY425769 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

MINA 293 Cell Lysate - 404128 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

MINA Overexpression Lysate (Native) - NBL1-13111 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

MINA Over-expression Lysate Product - GWB-706C0C from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

MINA Overexpression Lysate (Native) - NBP2-10899 from Novus Biologicals Category Cell Lysate Prices $529.00 Sizes 100 µg

MINA Overexpression Lysate (Native) - NBP2-11194 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

MINA Overexpression Lysate (Denatured) - H00084864-T01 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

Panoply™ Human MINA Knockdown Stable Cell Line - CSC-DC009524 from Creative biogene Category Cell Line Species Human

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