Gene Symbol | SENP8 |
---|---|
Entrez Gene | 123228 |
Alt Symbol | DEN1, NEDP1, PRSC2 |
Species | Human |
Gene Type | protein-coding |
Description | SUMO/sentrin specific peptidase family member 8 |
Other Description | NEDD8 specific-protease cysteine 2|NEDD8-specific protease 1|SUMO sentrin specific protease family member 8|deneddylase 1|deneddylase-1|protease, cysteine 2|sentrin-specific protease 8 |
Swissprots | Q96LD8 Q96QA4 |
Accessions | CAK32309 EAW77881 Q96LD8 AF308450 AAL06294 AK097557 AK292298 BAF84987 AY008293 AAG21828 BC031411 AAH31411 BP370384 CN367895 DB033241 DB048641 DQ890802 ABM81728 DQ893957 ABM84883 XM_005254157 XP_005254214 XM_011521215 XP_011519517 XM_011521216 XP_011519518 XM_011521217 XP_011519519 NM_001166340 NP_001159812 NM_001172109 NP_001165580 NM_001172110 NP_001165581 NM_001172111 NP_001165582 NM_145204 NP_660205 |
Function | Protease that catalyzes two essential functions in the NEDD8 pathway: processing of full-length NEDD8 to its mature form and deconjugation of NEDD8 from targeted proteins such as cullins or p53. {ECO:0000269|PubMed:12730221, ECO:0000269|PubMed:12759362, ECO:0000269|PubMed:12759363, ECO:0000269|PubMed:15242646, ECO:0000269|PubMed:15775960}. |
Tissue Specificity | Broadly expressed, with highest levels in kidney and pancreas. {ECO:0000269|PubMed:12730221}. |
SENP8 CRISPR/Cas9 KO Plasmid (h) - sc-405158 from Santa Cruz Biotechnology
|
||||||||
SENP8 HDR Plasmid (h) - sc-405158-HDR from Santa Cruz Biotechnology
|
||||||||
SENP8 Double Nickase Plasmid (h) - sc-405158-NIC from Santa Cruz Biotechnology
|
||||||||
SENP8 Double Nickase Plasmid (h2) - sc-405158-NIC-2 from Santa Cruz Biotechnology
|
||||||||
SENP8 CRISPR Activation Plasmid (h) - sc-405158-ACT from Santa Cruz Biotechnology
|
||||||||
SENP8 CRISPR Activation Plasmid (h2) - sc-405158-ACT-2 from Santa Cruz Biotechnology
|
||||||||
SENP8 Lentiviral Activation Particles (h) - sc-405158-LAC from Santa Cruz Biotechnology
|
||||||||
SENP8 Lentiviral Activation Particles (h2) - sc-405158-LAC-2 from Santa Cruz Biotechnology
|
||||||||
SENP8 siRNA (h) - sc-44452 from Santa Cruz Biotechnology
|
||||||||
SENP8 shRNA Plasmid (h) - sc-44452-SH from Santa Cruz Biotechnology
|
||||||||
SENP8 shRNA (h) Lentiviral Particles - sc-44452-V from Santa Cruz Biotechnology
|
||||||||
MISSION® esiRNA - EHU154551 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN19091 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19091 from Sigma-Aldrich
|
||||||||
SENP8 siRNA (Human) - CRJ4728 from Cohesion Biosciences
|
||||||||
NEDP1/SENP8 RNAi - H00123228-R01 from Novus Biologicals
|
||||||||
SENP8 - MBS8240813 from MyBioSource
|
||||||||
shRNA set against Human SENP8 (NM_145204.3) - SHH404528 from Creative biogene
|
||||||||
Human SENP8 siRNA - orb275229 from Biorbyt
|
||||||||
SENP8 shRNA Plasmid (Human) - CHJ4728 from Cohesion Biosciences
|
||||||||
SENP8 miRNA 3'UTR clone - MiUTR3H-10134 from Creative biogene
|