SENP8

Gene Symbol SENP8
Entrez Gene 123228
Alt Symbol DEN1, NEDP1, PRSC2
Species Human
Gene Type protein-coding
Description SUMO/sentrin specific peptidase family member 8
Other Description NEDD8 specific-protease cysteine 2|NEDD8-specific protease 1|SUMO sentrin specific protease family member 8|deneddylase 1|deneddylase-1|protease, cysteine 2|sentrin-specific protease 8
Swissprots Q96LD8 Q96QA4
Accessions CAK32309 EAW77881 Q96LD8 AF308450 AAL06294 AK097557 AK292298 BAF84987 AY008293 AAG21828 BC031411 AAH31411 BP370384 CN367895 DB033241 DB048641 DQ890802 ABM81728 DQ893957 ABM84883 XM_005254157 XP_005254214 XM_011521215 XP_011519517 XM_011521216 XP_011519518 XM_011521217 XP_011519519 NM_001166340 NP_001159812 NM_001172109 NP_001165580 NM_001172110 NP_001165581 NM_001172111 NP_001165582 NM_145204 NP_660205
Function Protease that catalyzes two essential functions in the NEDD8 pathway: processing of full-length NEDD8 to its mature form and deconjugation of NEDD8 from targeted proteins such as cullins or p53. {ECO:0000269|PubMed:12730221, ECO:0000269|PubMed:12759362, ECO:0000269|PubMed:12759363, ECO:0000269|PubMed:15242646, ECO:0000269|PubMed:15775960}.
Tissue Specificity Broadly expressed, with highest levels in kidney and pancreas. {ECO:0000269|PubMed:12730221}.

SENP8 (E-11) - sc-271498 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
SENP8 (E-11): sc-271498. Western blot analysis of SENP8 expression in Caki-1 (A) and MIA PaCa-2 (B) whole cell lysates.

SENP8 (F-20) - sc-46645 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

SENP8 (FL-212) - sc-67077 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
SENP8 (FL-212): sc-67077. Western blot analysis of SENP8 expression in non-transfected: sc-117752 (A) and human SENP8 transfected: sc-174054 (B) 293T whole cell lysates.

SENP8 (C-16) - sc-46643 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-SENP8 antibody - ab168601 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-SENP8 antibody (ab168601) at 1 µg/mlLane 1 : Lysate of 293T cells transfected with SENP8 Lane 2 : Lysate of untransfected 293T cellsLysates/proteins at 15 µl per lane.

Anti-SENP8 antibody - ab58423 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ab58423 at 1/50 dilution staining SENP8 in human breast carcinoma by Immunohistochemistry, Paraffin embedded tissue, in the absence or presence of the immunising peptide.

Anti-SENP8 antibody - ab77055 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Anti-SENP8 antibody (ab77055) at 1/500 dilution + recombinant SENP8 protein fragment(the immunogen) at 0.2 µgSecondaryGoat anti-mouse IgG (H&L)- HRP conjugate at 1/5000 dilution

Anti-SENP8 antibody - ab5279 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-SENP8 antibody - C-terminal - ab166815 from Abcam

Host Rabbit
Clonality Polyclonal
All lanes : Anti-SENP8 antibody - C-terminal (ab166815) at 1/500 dilutionLane 1 : HUVEC cell lysateLane 2 : HUVEC cell lysate with synthesized peptide

Anti-SENP8 antibody - N-terminal - ab137439 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-SENP8 antibody - N-terminal (ab137439) at 1/1000 dilution + Raji whole cell lysate at 30 µg

Anti-SENP8 Antibody - LS-C91288 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-SENP8 Antibody (aa196-211) - LS-C147889 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-SENP8 Antibody (N-Terminus, AP) - LS-C282578 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SENP8 Antibody (N-Terminus, APC) - LS-C282581 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SENP8 Antibody (N-Terminus, Biotin) - LS-C282582 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SENP8 Antibody (N-Terminus, FITC) - LS-C282583 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SENP8 Antibody (N-Terminus, PE) - LS-C282585 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SENP8 Antibody (N-Terminus) - LS-C328624 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SENP8 Antibody (N-Terminus, Azide-free, HRP) - LS-C282584 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SENP8 Antibody (clone 3E4) - LS-C339304 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 3E4
IHC of paraffin-embedded Human thyroid tissue using anti-SENP8 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).

Anti-SENP8 Antibody (aa101-150) - LS-C206202 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
SENP8 antibody Western Blot of 786-0. Antibody dilution: 1 ug/ml.

Anti-SENP8 Antibody (Thr191) - LS-C176351 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC of SENP8 (T191) pAb in paraffin-embedded human breast carcinoma tissue.

Anti-SENP8 Antibody (aa4-35) - LS-C98811 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot of SENP8 (arrow) using rabbit polyclonal SENP8 Antibody (S19). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the SENP8 gene.

Anti-SENP8 Antibody (aa161-210) IHC-plus™ - LS-B8394 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-SENP8 antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B8394 dilution 5 ug/ml.

NEDP1/SENP8 Antibody - AF7760 from Novus Biologicals

Prices $99.00, $359.00
Sizes 25 µg, 100 µg
Host Sheep
Clonality Polyclonal
Western blot shows lysates of JAR human choriocarcinoma cell line, beta TC‑6 mouse beta cell insulinoma cell line, and NRK‑49F rat fibroblasts. PVDF membrane was probed with 1 µg/mL of Sheep Anti-Human/Mouse/Rat NEDP1/SENP8 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF7760) followed by HRP-conjugated Anti-Sheep IgG Secondary Antibody (Catalog # HAF016). A specific band was detected for NEDP1/SENP8 at approximately 24 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.
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