OPHN1

Gene Symbol	OPHN1
Entrez Gene	4983
Alt Symbol	ARHGAP41, MRX60, OPN1
Species	Human
Gene Type	protein-coding
Description	oligophrenin 1
Other Description	mental retardation, X-linked 60|oligophrenin-1|oligophrenin-1, Rho-GTPase activating protein
Swissprots	B9EIP8 Q6PCC1 Q8WX47 O60890 Q5JQ81
Accessions	BAC80690 BAC80691 BAC80692 BAC80693 BAC80694 BAC80695 BAC80696 BAC80697 BAC80698 BAC80699 BAC80700 BAC80701 BAC80702 BAC80703 BAC80704 BAC80705 BAC80706 BAC80707 BAC80708 BAC80709 CAB96181 CAC07882 EAX05378 O60890 AB102656 BAC81125 AJ001189 CAA04579 AK295769 BAG58594 AK309665 AK309696 BC059393 AAH59393 BC140763 AAI40764 BP357826 XM_005262270 XP_005262327 XM_006724653 XP_006724716 XM_011530961 XP_011529263 NM_002547 NP_002538
Function	Stimulates GTP hydrolysis of members of the Rho family. Its action on RHOA activity and signaling is implicated in growth and stabilization of dendritic spines, and therefore in synaptic function. Critical for the stabilization of AMPA receptors at postsynaptic sites. Critical for the regulation of synaptic vesicle endocytosis at presynaptic terminals. Required for the localization of NR1D1 to dendrites, can suppress its repressor activity and protect it from proteasomal degradation (By similarity). {ECO:0000250}.
Subcellular Location	Cell junction, synapse. Cell projection, axon. Cell projection, dendritic spine. Cell projection, dendrite {ECO:0000250}. Cytoplasm {ECO:0000250}. Note=Present in both presynaptic and postsynaptic sites. {ECO:0000250}.
Tissue Specificity	Expressed in brain.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human OPHN1 full length protein - ab159026 from Abcam Category Protein Source Wheat germ Species Human

Human OPHN1 protein fragment - ab159027 from Abcam Category Protein Source Wheat germ Species Human

Recombinant Human OPHN1 Protein - H00004983-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human OPHN1 Protein - H00004983-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Oligophrenin-1 - H00004983-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

Oligophrenin-1 - H00004983-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

Oligophrenin-1 - H00004983-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

Oligophrenin-1 - H00004983-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

OPHN1 fusion protein - ag1224 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

OPHN1 fusion protein - Ag11488 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

OPHN1 fusion protein - ag11538 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

OPHN1 fusion protein - ag1536 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human Oligophrenin-1(OPHN1) ,partial - CSB-YP016348HU CSB-EP016348HU CSB-BP016348HU CSB-MP016348HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

OPHN1 Protein - abx164261 from Abbexa Category Protein Species Human, Mouse, Rat

Oligophrenin-1 - TP314215 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

Recombinant Oligophrenin 1 (OPHN1) - RPC691Mu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

Recombinant Oligophrenin 1 (OPHN1) - RPC691Ra01 from Uscn Life Science Inc. Category Protein Source E.coli Species Rat

OPHN1 Protein - NBP1-88828PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

OPHN1-Blocking-Peptide-Center - BP21819c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

OPHN1 Peptide, Human - M34GP10853H from Creative Peptides Category Peptide Source Synthetic. Species Human

Oligophrenin 1, Recombinant Protein - MBS2034195 from MyBioSource Category Protein Prices $170.00, $340.00, $530.00 Sizes 10 µg, 50 µg, 100 µg Source Prokaryotic Expression Species Mouse

Oligophrenin 1, Recombinant Protein - MBS2034429 from MyBioSource Category Protein Prices $170.00, $340.00, $530.00 Sizes 10 µg, 50 µg, 100 µg Source Prokaryotic Expression Species Rat

Oligophrenin-1 (OPHN1), partial, Recombinant Protein - MBS1040429 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

OPHN1 fusion protein - Ag27300 from Proteintech Group Category Protein Source E. coli -derived, PET28a Species Human

Recombinant Human OPHN1 Protein, MYC/DDK-tagged - OPHN1-297H from Creative Biomart Category Protein Source HEK293 Species Human

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