ADAM22

Gene Symbol	ADAM22
Entrez Gene	53616
Alt Symbol	ADAM 22, MDC2
Species	Human
Gene Type	protein-coding
Description	ADAM metallopeptidase domain 22
Other Description	a disintegrin and metalloproteinase domain 22|disintegrin and metalloproteinase domain-containing protein 22|metalloproteinase-disintegrin ADAM22-3|metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2
Swissprots	Q9UKK2 Q9P0K2 O75076 O75075 Q9UIA1 Q9P0K1
Accessions	AAD55253 AAP21878 AAS07417 EAW76913 EAW76914 EAW76915 EAW76916 EAW76917 EAW76918 EAW76919 EAW76920 EAW76921 EAW76922 EAW76923 EAW76924 EAW76925 EAW76926 EAW76927 EAW76928 EAW76929 Q9P0K1 AB009671 BAA32349 AF073291 AAF22476 AF155381 AAF73288 AF155382 AAF73289 AF158637 AAD55251 AK125432 BAG54196 AK291010 BAF83699 AL133090 BC036029 AAH36029 BC062433 AAH62433 BC092465 AAH92465 BC125117 BC125118 AAI25119 CA429662 DR000609 XM_005250445 XP_005250502 XM_006716028 XP_006716091 XM_006716029 XP_006716092 XM_011516318 XP_011514620 XM_011516319 XP_011514621 XM_011516320 XP_011514622 XM_011516321 XP_011514623 XM_011516322 XP_011514624 XM_011516323 XP_011514625 XM_011516324 XP_011514626 NM_004194 NP_004185 NM_016351 NP_057435 NM_021721 NP_068367 NM_021722 NP_068368 NM_021723 NP_068369
Function	Probable ligand for integrin in the brain. This is a non catalytic metalloprotease-like protein (PubMed:19692335). Involved in regulation of cell adhesion and spreading and in inhibition of cell proliferation. Neuronal receptor for LGI1. {ECO:0000269|PubMed:12589811, ECO:0000269|PubMed:15882968, ECO:0000269|PubMed:16385342, ECO:0000269|PubMed:19692335}.
Subcellular Location	Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. Cell projection, axon {ECO:0000250|UniProtKB:Q9R1V6}.
Tissue Specificity	Highly expressed in the brain and in some high-grade but not low-grade gliomas. Detected slightly or not at all in other tissues. {ECO:0000269|PubMed:16385342}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human ADAM22 full length protein - ab153364 from Abcam Category Protein Source Wheat germ Species Human

ADAM22 Antibody Blocking Peptide - LS-E16918 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human ADAM22 Protein - H00053616-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human ADAM22, CF - 4908-AD-050 from R&D Systems Category Protein Source Chinese Hamster Ovary cell line, CHO-derived, Gly26-His528 (Leu78Val), with a C-terminal 8-His tag

Adam22 Blocking Peptide - 33R-1280 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

ADAM22 / MDC2 - H00053616-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

ADAM22 / MDC2 - H00053616-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

ADAM22 fusion protein - ag5211 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

ADAM22 fusion protein - ag5721 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

Recombinant A Disintegrin And Metalloprotease 22 (ADAM22) - RPK165Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant A Disintegrin And Metalloprotease 22 (ADAM22) - RPK165Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Human Disintegrin and metalloproteinase domain-containing protein 22 - CSB-YP865198HU CSB-EP865198HU CSB-BP865198HU CSB-MP865198HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Recombinant Human ADAM22 Protein, CF - 4908-AD from R&D Systems Category Protein Prices $329.00 Sizes 50 µg Source Chinese Hamster Ovary cell line, CHO-derived Gly26-His528 (Leu78Val), with a C-terminal 8-His tag Species Human

ADAM22 Protein - NBP2-14264PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

ADAM22-Antibody-N-term-Blocking-peptide - BP10118a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

ADAM22 Peptide, Human - M34GP00238H from Creative Peptides Category Peptide Source Synthetic. Species Human

ADAM22 Recombinant Protein (OPCD00860) - OPCD00860 from Aviva Systems Biology Category Protein Source E.coli Species Human

ADAM22 Recombinant Protein Antigen - NBP2-58310PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

Disintegrin and metalloproteinase domain-containing protein 22 (ADAM22), Recombinant Protein - MBS1469950 from MyBioSource Category Protein Prices $1,305.00, $1,305.00, $1,525.00, $1,525.00, $2,145.00, $2,145.00, $2,610.00, $2,610.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

ADAM22 fusion protein - Ag26812 from Proteintech Group Category Protein Source E. coli -derived, PET28a Species Human

Recombinant Human ADAM22 Protein, CF - 4908-AD from Novus Biologicals Category Protein Prices $329.00 Sizes 50 µg Species Human

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