Gene Symbol | BTBD10 |
---|---|
Entrez Gene | 84280 |
Alt Symbol | GMRP-1, GMRP1 |
Species | Human |
Gene Type | protein-coding |
Description | BTB (POZ) domain containing 10 |
Other Description | BTB (broad-complex tramtrack and bric-a-brac/pox virus and zinc finger) domain-containing protein 10|BTB/POZ domain-containing protein 10|K+ channel tetramerization protein|glucose metabolism-related protein 1 |
Swissprots | Q86WG1 Q9BSF8 B7Z228 |
Accessions | EAW68497 EAW68498 EAW68499 EAW68500 EAW68501 EAW68502 Q9BSF8 AF329102 AAL69061 AI051522 AK095946 AK292392 BAF85081 AK294259 BAH11714 AK294768 BAH11877 AK298226 BAH12739 AK310935 AK316163 BAH14534 AL832981 CAH56329 AY221959 AAO64360 BC005071 AAH05071 BC017072 AAH17072 BC062633 AAH62633 DB030132 EU831955 ACE87396 EU832049 ACE86711 XM_005253165 XP_005253222 XM_006718345 XP_006718408 XM_011520404 XP_011518706 NM_001297741 NP_001284670 NM_001297742 NP_001284671 NM_032320 NP_115696 |
Function | Plays a major role as an activator of AKT family members by inhibiting PPP2CA-mediated dephosphorylation, thereby keeping AKTs activated. Plays a role in preventing motor neuronal death and accelerating the growth of pancreatic beta cells. {ECO:0000250|UniProtKB:Q80X66}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:15556295}. Cytoplasm {ECO:0000250|UniProtKB:Q80X66}. Note=Colocalizes with KCTD20 in filamentous structures. {ECO:0000250|UniProtKB:Q80X66}. |
Tissue Specificity | Ubiquitously expressed. Highly expressed in adult brain, testis, aorta and small intestine and weakly expressed in the heart, lung, liver, kidney, pancreas, spleen, thymus, prostate, ovary and colon. Down-regulated in glioma. {ECO:0000269|PubMed:15556295, ECO:0000269|PubMed:21267538}. |
BTBD10 / GMRP-1 Antibody Blocking Peptide - LS-E12578 from LifeSpan Bioscience
|
||||||||||
BTBD10 / GMRP-1 Antibody Blocking Peptide - LS-E10152 from LifeSpan Bioscience
|
||||||||||
BTBD10-Antibody-Center-Blocking-Peptide - BP9476c from Abgent, a WuXi AppTec company
|
||||||||||
BTBD10 Blocking Peptide - 33R-1218 from Fitzgerald
|
||||||||||
BTBD10 fusion protein - ag10684 from Proteintech Group
|
||||||||||
BTBD10 fusion protein - Ag10667 from Proteintech Group
|
||||||||||
Recombinant Human BTBD10, His-tagged - BTBD10-26109TH from Creative Biomart
|
||||||||||
Recombinant Human BTB/POZ domain-containing protein 10(BTBD10) - CSB-YP874798HU CSB-EP874798HU CSB-BP874798HU CSB-MP874798HU from Cusabio
|
||||||||||
BTBD10 (full length, N-term HIS tag) - TP760066 from Acris Antibodies
|
||||||||||
BTBD10 Recombinant Protein Antigen - NBP2-38558PEP from Novus Biologicals
|
||||||||||
BTBD10 Peptide, Human - M34GP01562H from Creative Peptides
|
||||||||||
BTB/POZ domain-containing protein 10 (BTBD10), Recombinant Protein - MBS1432934 from MyBioSource
|