BTBD10

Gene Symbol BTBD10
Entrez Gene 84280
Alt Symbol GMRP-1, GMRP1
Species Human
Gene Type protein-coding
Description BTB (POZ) domain containing 10
Other Description BTB (broad-complex tramtrack and bric-a-brac/pox virus and zinc finger) domain-containing protein 10|BTB/POZ domain-containing protein 10|K+ channel tetramerization protein|glucose metabolism-related protein 1
Swissprots Q86WG1 Q9BSF8 B7Z228
Accessions EAW68497 EAW68498 EAW68499 EAW68500 EAW68501 EAW68502 Q9BSF8 AF329102 AAL69061 AI051522 AK095946 AK292392 BAF85081 AK294259 BAH11714 AK294768 BAH11877 AK298226 BAH12739 AK310935 AK316163 BAH14534 AL832981 CAH56329 AY221959 AAO64360 BC005071 AAH05071 BC017072 AAH17072 BC062633 AAH62633 DB030132 EU831955 ACE87396 EU832049 ACE86711 XM_005253165 XP_005253222 XM_006718345 XP_006718408 XM_011520404 XP_011518706 NM_001297741 NP_001284670 NM_001297742 NP_001284671 NM_032320 NP_115696
Function Plays a major role as an activator of AKT family members by inhibiting PPP2CA-mediated dephosphorylation, thereby keeping AKTs activated. Plays a role in preventing motor neuronal death and accelerating the growth of pancreatic beta cells. {ECO:0000250|UniProtKB:Q80X66}.
Subcellular Location Nucleus {ECO:0000269|PubMed:15556295}. Cytoplasm {ECO:0000250|UniProtKB:Q80X66}. Note=Colocalizes with KCTD20 in filamentous structures. {ECO:0000250|UniProtKB:Q80X66}.
Tissue Specificity Ubiquitously expressed. Highly expressed in adult brain, testis, aorta and small intestine and weakly expressed in the heart, lung, liver, kidney, pancreas, spleen, thymus, prostate, ovary and colon. Down-regulated in glioma. {ECO:0000269|PubMed:15556295, ECO:0000269|PubMed:21267538}.

BTBD10 CRISPR/Cas9 KO Plasmid (h) - sc-413609 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

BTBD10 HDR Plasmid (h) - sc-413609-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

BTBD10 Double Nickase Plasmid (h) - sc-413609-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

BTBD10 Double Nickase Plasmid (h2) - sc-413609-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

BTBD10 CRISPR Activation Plasmid (h) - sc-413609-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

BTBD10 CRISPR Activation Plasmid (h2) - sc-413609-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

BTBD10 Lentiviral Activation Particles (h) - sc-413609-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

BTBD10 Lentiviral Activation Particles (h2) - sc-413609-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

BTBD10 siRNA (h) - sc-96459 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

BTBD10 shRNA Plasmid (h) - sc-96459-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

BTBD10 shRNA (h) Lentiviral Particles - sc-96459-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

BTBD10 RNAi - H00084280-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU111191 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN4086 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND4086 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR06606 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr06606

BTBD10 siRNA (Human) - CRJ3405 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

BTBD10 - MBS8207685 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human BTBD10 (NM_032320.5) - SHH248066 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human BTBD10(NM_032320.5) - SHG106479 from Creative biogene

Category siRNA
Species Reactivities Human

Human BTBD10 siRNA - orb273906 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

BTBD10 shRNA Plasmid (Human) - CHJ3405 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

BTBD10 miRNA 3'UTR clone - MiUTR1H-00964 from Creative biogene

Species Reactivities Human
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