BTBD10

Gene Symbol BTBD10
Entrez Gene 84280
Alt Symbol GMRP-1, GMRP1
Species Human
Gene Type protein-coding
Description BTB (POZ) domain containing 10
Other Description BTB (broad-complex tramtrack and bric-a-brac/pox virus and zinc finger) domain-containing protein 10|BTB/POZ domain-containing protein 10|K+ channel tetramerization protein|glucose metabolism-related protein 1
Swissprots Q86WG1 Q9BSF8 B7Z228
Accessions EAW68497 EAW68498 EAW68499 EAW68500 EAW68501 EAW68502 Q9BSF8 AF329102 AAL69061 AI051522 AK095946 AK292392 BAF85081 AK294259 BAH11714 AK294768 BAH11877 AK298226 BAH12739 AK310935 AK316163 BAH14534 AL832981 CAH56329 AY221959 AAO64360 BC005071 AAH05071 BC017072 AAH17072 BC062633 AAH62633 DB030132 EU831955 ACE87396 EU832049 ACE86711 XM_005253165 XP_005253222 XM_006718345 XP_006718408 XM_011520404 XP_011518706 NM_001297741 NP_001284670 NM_001297742 NP_001284671 NM_032320 NP_115696
Function Plays a major role as an activator of AKT family members by inhibiting PPP2CA-mediated dephosphorylation, thereby keeping AKTs activated. Plays a role in preventing motor neuronal death and accelerating the growth of pancreatic beta cells. {ECO:0000250|UniProtKB:Q80X66}.
Subcellular Location Nucleus {ECO:0000269|PubMed:15556295}. Cytoplasm {ECO:0000250|UniProtKB:Q80X66}. Note=Colocalizes with KCTD20 in filamentous structures. {ECO:0000250|UniProtKB:Q80X66}.
Tissue Specificity Ubiquitously expressed. Highly expressed in adult brain, testis, aorta and small intestine and weakly expressed in the heart, lung, liver, kidney, pancreas, spleen, thymus, prostate, ovary and colon. Down-regulated in glioma. {ECO:0000269|PubMed:15556295, ECO:0000269|PubMed:21267538}.

BTBD10 (B-1) - sc-377183 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
BTBD10 (B-1): sc-377183. Western blot analysis of BTBD10 expression in PC-3 nuclear extract (A) and LADMAC whole cell lysate (B).

BTBD10 (N-12) - sc-160978 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
BTBD10 (N-12): sc-160978. Western blot analysis of BTBD10 expression in mouse brain tissue extract (A) and LADMAC (B) and WI 38 (C) whole cell lysates.

BTBD10 (T-14) - sc-160979 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
BTBD10 (T-14): sc-160979. Western blot analysis of BTBD10 expression in PC-3 nuclear extract.

Anti-BTBD10 antibody - ab126060 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-BTBD10 antibody (ab126060) at 1/1000 dilution + NT2D1 whole cell lysate at 30 µg

Anti-BTBD10 antibody - ab102772 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-BTBD10 antibody (ab102772) at 1/100 dilution + K562 cell line lysates at 35 µg

Anti-BTBD10 antibody - ab83085 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-BTBD10 antibody (ab83085) at 1 µg/ml + 293T cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilutionObserved band size : 54 kDa (why is the actual band size different from the predicted?)

Anti-BTBD10 antibody - ab167236 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-BTBD10 antibody (ab167236) at 1 µg/mlLane 1 : BTBD10 transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 15 µl per lane.SecondaryGoat anti-Mouse IgG HRP at 1/2500 dilution

Anti-BTBD10 / GMRP-1 Antibody (aa191-218, APC) - LS-C208147 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BTBD10 / GMRP-1 Antibody (aa191-218, AP) - LS-C208146 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BTBD10 / GMRP-1 Antibody (aa191-218, FITC) - LS-C208150 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BTBD10 / GMRP-1 Antibody (aa191-218, Biotin) - LS-C208149 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BTBD10 / GMRP-1 Antibody (aa191-218, Azide-free, HRP) - LS-C208151 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BTBD10 / GMRP-1 Antibody (aa191-218, PE) - LS-C208152 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BTBD10 / GMRP-1 Antibody - LS-C306585 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-BTBD10 / GMRP-1 Antibody (aa197-227) - LS-C319893 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BTBD10 / GMRP-1 Antibody (N-Terminus) - LS-C101542 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
BTBD10 antibody LS-C101542 Western blot of 293T cell lysate.

Anti-BTBD10 / GMRP-1 Antibody - LS-C155290 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Sample (50 ug of whole cell lysate) A: mouse testis 10% SDS PAGE BTBD10 antibody diluted at 1:500

Anti-BTBD10 / GMRP-1 Antibody (aa191-218) - LS-C156875 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot of BTBD10 Antibody in K562 cell line lysates (35 ug/lane). BTBD10 (arrow) was detected using the purified antibody.

BTBD10 Antibody - NBP2-38558 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: BTBD10 Antibody [NBP2-38558] - Immunofluorescent staining of human cell line MCF7 shows localization to nucleus & nucleoli fibrillar center.

BTBD10 Antibody - NBP2-15625 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: BTBD10 Antibody [NBP2-15625] - Sample (50 ug of whole cell lysate) A: Mouse Testis, 10% SDS PAGE gel, diluted at 1:500.

BTBD10 Antibody - NBP1-80088 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal

BTBD10 Antibody - H00084280-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: BTBD10 Antibody [H00084280-B01] - analysis of BTBD10 expression in transfected 293T cell line by BTBD10 MaxPab polyclonal antibody. Lane 1: BTBD10 transfected lysate (52.25 KDa). Lane 2: Non-transfected lysate.

BTBD10 Antibody - H00084280-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

GMRP1 Polyclonal Antibody - bs-8157R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

BTBD10 Polyclonal Antibody - bs-8398R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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