VIPR2

Gene Symbol VIPR2
Entrez Gene 7434
Alt Symbol C16DUPq36.3, DUP7q36.3, PACAP-R-3, PACAP-R3, VIP-R-2, VPAC2, VPAC2R, VPCAP2R
Species Human
Gene Type protein-coding
Description vasoactive intestinal peptide receptor 2
Other Description PACAP type III receptor|VIP and PACAP receptor 2|helodermin-preferring VIP receptor|pituitary adenylate cyclase-activating polypeptide type III receptor|vasoactive intestinal polypeptide receptor 2
Swissprots P41587 Q13053 Q6ZN22 Q9UCW0 Q53Y09 Q15870
Accessions AAC09171 AAC41756 CAB41899 EAL23936 EAL23937 EAX04596 P41587 AK131406 BAD18553 AK308955 AK310386 BC010569 AAH10569 BT007118 AAP35782 CA449700 DQ890571 ABM92188 DQ893732 ABM84658 KJ534960 AHW56600 KJ534961 AHW56601 KJ534970 AHW56610 L36566 AAC37569 U18810 AAC50872 X95097 CAA64474 XM_005249561 XP_005249618 XM_006716107 XP_006716170 XM_006716108 XP_006716171 XM_011516550 XP_011514852 XM_011516551 XP_011514853 XM_011516552 XP_011514854 XR_242047 NM_001304522 NP_001291451 NM_001308259 NP_001295188 NM_003382 NP_003373 NR_130758
Function This is a receptor for VIP as well as PACAP-38 and -27, the activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Can be coupled to phospholipase C. {ECO:0000269|PubMed:8926282}.
Subcellular Location Cell membrane; Multi-pass membrane protein.
Tissue Specificity Expressed in CD4+ T-cells, but not in CD8+ T- cells. Expressed in the T-cell lines Jurkat, Peer, MOLT-4, HSB, YT and SUP-T1, but not in the T-cell lines HARRIS and HuT 78. {ECO:0000269|PubMed:8926282}.
Top Pathways cAMP signaling pathway, Neuroactive ligand-receptor interaction

VPAC2 (K-15) - sc-15960 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

VPAC2 (N-19) - sc-15961 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

VPAC2 (H-50) - sc-30020 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

VPAC2 (5B3) - sc-135604 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
VPAC2 (5B3): sc-135604. Western blot analysis of VPAC2 expression in IMR-32 whole cell lysate.

VPAC2 (AS69) - sc-52795 from Santa Cruz Biotechnology

Prices $279.00
Sizes 50 µg/500 µl
Host Mouse
Clonality Monoclonal

Anti-VPAC2 antibody - ab28624 from Abcam

Prices $379.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
ab28624 staining Human VIP Receptor 2 in human neuroendocrine cells of the small intestine by immunohistochemistry using paraffin embedded tissue.

Anti-VPAC2 antibody - ab194383 from Abcam

Prices $376.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Anti-VPAC2 antibody (ab194383) at 1/1000 dilution + recombinant VPAC2 protein fragment (immunogen) at 0.2 µg

Anti-VPAC2 antibody - ab130658 from Abcam

Prices $376.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
IHC image of VPAC2 staining in human skeletal muscle formalin fixed paraffin embedded tissue section, performed on a Leica Bond system using the standard protocol F. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH6, epitope retrieval solution 1) for 20 mins. The section was then incubated with ab130658, 5µg/ml, for 15 mins at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.For other IHC staining systems (automated and non-automated) customers should optimize variable parameters such as antigen retrieval conditions, primary antibody concentration and antibody incubation times.

Anti-VPAC2 antibody - ab96608 from Abcam

Prices $376.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-VPAC2 antibody (ab96608) at 1/1000 dilution + HeLa whole cell lysate at 30 µg

Anti-VPAC2 antibody [SP235] - ab183334 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone SP235
Flow cytometric analysis of Jurkat cells labeling VPAC2 using ab183334 (green) compare to negative control of rabbit IgG (blue)

Anti-VPAC2 / VIPR2 Antibody (aa24-127) - LS-C132872 from LifeSpan Bioscience

Prices $445.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-VPAC2 / VIPR2 Antibody (aa3-14) - LS-C132874 from LifeSpan Bioscience

Prices $395.00
Sizes 20 µl
Host Rabbit
Clonality Polyclonal

Anti-VPAC2 / VIPR2 Antibody (aa1-12) - LS-C132873 from LifeSpan Bioscience

Prices $355.00
Sizes 20 µl
Host Rabbit
Clonality Polyclonal

Anti-VPAC2 / VIPR2 Antibody (clone 2G9) - LS-C139251 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2G9

Anti-VPAC2 / VIPR2 Antibody (Internal) - LS-C145080 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-VPAC2 / VIPR2 Antibody (Internal) - LS-C153593 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-VPAC2 / VIPR2 Antibody (C-Terminus) IHC-plus™ - LS-A1305 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-VPAC2 / VIPR2 antibody IHC of human Pancreas, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-VPAC2 / VIPR2 Antibody (C-Terminus) IHC-plus™ - LS-A1306 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-VPAC2 / VIPR2 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-VPAC2 / VIPR2 Antibody (aa95-123, AP) - LS-C218426 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-VPAC2 / VIPR2 Antibody (aa95-123, APC) - LS-C218427 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-VPAC2 / VIPR2 Antibody - LS-C27046 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
IHC of rat hippocampus stained with VIPR2 antibody (LS-C27046) at 5 ug/ml.

Anti-VPAC2 / VIPR2 Antibody (aa95-123, Biotin) - LS-C218428 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-VPAC2 / VIPR2 Antibody (aa95-123, FITC) - LS-C218429 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-VPAC2 / VIPR2 Antibody (aa334-423) - LS-C185362 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Sample (30 ug of whole cell lysate). A: Hela. 10% SDS PAGE. VPAC2 / VIPR2 antibody diluted at 1:1000.

Anti-VPAC2 / VIPR2 Antibody (aa95-123, Azide-free, HRP) - LS-C218430 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
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