SMARCAL1

Gene Symbol SMARCAL1
Entrez Gene 50485
Alt Symbol HARP, HHARP
Species Human
Gene Type protein-coding
Description SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
Other Description ATP-driven annealing helicase|HepA-related protein|SMARCA-like protein 1|SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1|sucrose nonfermenting protein 2-like 1
Swissprots Q9UI93 Q9NXQ5 A6NEH0 Q53R00 Q96AY1 Q9NZC9 Q9UFH3
Accessions AAF70454 AAX93097 EAW70567 Q9NZC9 AF082179 AAF24984 AF432223 AAL73034 AI701066 AK000117 BAA90955 AK023780 AL122076 CAB59251 BC016482 AAH16482 BC029994 BC043341 AAH43341 BX104166 DA856812 DB099423 DQ891737 ABM82663 DQ894913 ABM85839 XM_005246631 XP_005246688 XM_005246632 XP_005246689 XM_006712557 XP_006712620 NM_001127207 NP_001120679 NM_014140 NP_054859
Function ATP-dependent annealing helicase that binds selectively to fork DNA relative to ssDNA or dsDNA and catalyzes the rewinding of the stably unwound DNA. Rewinds single-stranded DNA bubbles that are stably bound by replication protein A (RPA). Acts throughout the genome to reanneal stably unwound DNA, performing the opposite reaction of many enzymes, such as helicases and polymerases, that unwind DNA. May play an important role in DNA damage response by acting at stalled replication forks. {ECO:0000269|PubMed:18974355, ECO:0000269|PubMed:19793861, ECO:0000269|PubMed:19793862}.
Subcellular Location Nucleus {ECO:0000269|PubMed:19793862, ECO:0000269|PubMed:19793863}. Note=Recruited to damaged DNA regions.
Tissue Specificity Ubiquitously expressed, with high levels in testis. {ECO:0000269|PubMed:10857751, ECO:0000269|PubMed:11799392}.

SmarcAL1 (A-2) - sc-376377 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
SmarcAL1 (A-2): sc-376377. Western blot analysis of SmarcAL1 expression in non-transfected 293: sc-110760 (A), human SmarcAL1 transfected 293: sc-113334 (B) and DU 145 (C) whole cell lysates.

SmarcAL1 (E-12) - sc-166209 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
SmarcAL1 (E-12): sc-166209. Western blot analysis of SmarcAL1 expression in non-transfected: sc-117752 (A) and human SmarcAL1 transfected: sc-115969 (B) 293T whole cell lysates.

SmarcAL1 (K-20) - sc-54519 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
SmarcAL1 (K-20): sc-54519. Immunoperoxidase staining of formalin fixed, paraffin-embedded human nasopharynx tissue showing nuclear staining of respiratory epithelial cells.

SmarcAL1 (G-20) - sc-54518 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
SmarcAL1 (G-20): sc-54518. Western blot analysis of SmarcAL1 expression in non-transfected: sc-110760 (A) and human SmarcAL1 transfected: sc-113334 (B) 293 whole cell lysates.

SmarcAL1 (H-124) - sc-292681 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
SmarcAL1 (H-124): sc-292681. Western blot analysis of SmarcAL1 expression in non-transfected: sc-117752 (A) and human SmarcAL1 transfected: sc-113334 (B) 293T whole cell lysates.

SmarcAL1 (N-20) - sc-54468 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-SmarcAL1 antibody - ab115611 from Abcam

Prices $407.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ab115611, at 5µg/ml, staining SmarcAL1 in Formalin-fixed, Paraffin-embedded Human brain cortex tissue by Immunohistochemistry followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Anti-SmarcAL1 antibody - ab154226 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-SmarcAL1 antibody (ab154226) at 1/500 dilution + A549 whole cell lysate at 30 µg

Anti-SmarcAL1 antibody - ab169092 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-SmarcAL1 antibody (ab169092) at 1 µg/mlLane 1 : SmarcAL1-transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 15 µl per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP at 1/2500 dilutiondeveloped using the ECL technique

Anti-SmarcAL1 antibody - ab4743 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-SMARCAL1 Antibody (aa904-954) - LS-C286218 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-SMARCAL1 Antibody (N-Terminus) - LS-C345399 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of SMARCAL1 Antibody with human Lymph Node Tumor lysate.

Anti-SMARCAL1 Antibody (C-Terminus) - LS-C80248 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
721_B cell lysate. Antibody concentration: 1.25 ug/ml. Gel concentration: 8%.

Anti-SMARCAL1 Antibody (aa719-768) - LS-C109896 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
SMARCAL1 antibody LS-C109896 Western blot of Transfected 293T cell lysate.

Anti-SMARCAL1 Antibody (N-Terminus) - LS-C109895 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
SMARCAL1 antibody LS-C109895 Western blot of Transfected 293T cell lysate.

Anti-SMARCAL1 Antibody - LS-C332054 from LifeSpan Bioscience

Prices $305.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of Jurkat cell line, using SMARCAL1 antibody.

Anti-SMARCAL1 Antibody (aa74-123) - LS-C206186 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
SMARCAL1 antibody Western Blot of PANC1. Antibody dilution: 1 ug/ml.

Anti-SMARCAL1 Antibody (aa80-96) IHC-plus™ - LS-B423 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-SMARCAL1 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B423 concentration 5 ug/ml.

SmarcAL1 Antibody - NBP2-20414 from Novus Biologicals

Prices $349.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: SmarcAL1 Antibody [NBP2-20414] - A: A549.

SmarcAL1 Antibody - NBP2-13352 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: SmarcAL1 Antibody [NBP2-13352] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11<br/>Lane 2: Human cell line RT-4

SmarcAL1 Antibody - H00050485-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: SmarcAL1 Antibody [H00050485-B01P] - Analysis of SMARCAL1 expression in transfected 293T cell line by SMARCAL1 polyclonal antibody. Lane 1: SMARCAL1 transfected lysate(104.94 KDa). Lane 2: Non-transfected lysate.

SmarcAL1 Antibody - NB100-81640 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: SmarcAL1 Antibody [NB100-81640] - Detection of Human SMARCAL1 on HeLa whole cell lysate using NB100-81640. SMARCAL1 was also immunoprecipitated by another rabbit anti-SMARCAL1 antibody.

Anti-SMARCAL1, (N-terminal) antibody produced in rabbit - SAB2103073 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-SMARCAL1, antibody produced in rabbit: <B>Cat. No. SAB2103073</B>: Immunoblotting analysis of SMARCAL1 in transfected 293T cell lysate with SMARCAL1 anitbody at 1 μg/mL.

Anti-SMARCAL1 antibody produced in mouse - SAB1407412 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Anti-SMARCAL1: <B>Cat. No. SAB1407412</B>: Antibody concentration: 10 μg/mL using HeLa cell.

Anti-SMARCAL1 antibody produced in rabbit - SAB2103074 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-SMARCAL1, antibody produced in rabbit: <B>Cat. No. SAB2103074</B>: Immunoblotting analysis of SMARCAL1 in transfected 293T cell lysate with SMARCAL1 anitbody at 1 μg/mL.
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