SMARCAL1

Gene Symbol SMARCAL1
Entrez Gene 50485
Alt Symbol HARP, HHARP
Species Human
Gene Type protein-coding
Description SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
Other Description ATP-driven annealing helicase|HepA-related protein|SMARCA-like protein 1|SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1|sucrose nonfermenting protein 2-like 1
Swissprots Q9UI93 Q9NXQ5 A6NEH0 Q53R00 Q96AY1 Q9NZC9 Q9UFH3
Accessions AAF70454 AAX93097 EAW70567 Q9NZC9 AF082179 AAF24984 AF432223 AAL73034 AI701066 AK000117 BAA90955 AK023780 AL122076 CAB59251 BC016482 AAH16482 BC029994 BC043341 AAH43341 BX104166 DA856812 DB099423 DQ891737 ABM82663 DQ894913 ABM85839 XM_005246631 XP_005246688 XM_005246632 XP_005246689 XM_006712557 XP_006712620 NM_001127207 NP_001120679 NM_014140 NP_054859
Function ATP-dependent annealing helicase that binds selectively to fork DNA relative to ssDNA or dsDNA and catalyzes the rewinding of the stably unwound DNA. Rewinds single-stranded DNA bubbles that are stably bound by replication protein A (RPA). Acts throughout the genome to reanneal stably unwound DNA, performing the opposite reaction of many enzymes, such as helicases and polymerases, that unwind DNA. May play an important role in DNA damage response by acting at stalled replication forks. {ECO:0000269|PubMed:18974355, ECO:0000269|PubMed:19793861, ECO:0000269|PubMed:19793862}.
Subcellular Location Nucleus {ECO:0000269|PubMed:19793862, ECO:0000269|PubMed:19793863}. Note=Recruited to damaged DNA regions.
Tissue Specificity Ubiquitously expressed, with high levels in testis. {ECO:0000269|PubMed:10857751, ECO:0000269|PubMed:11799392}.

Human SmarcAL1 full length protein - ab162336 from Abcam

Category Protein
Source Wheat germ
Species Human
ab162336 on a 12.5% SDS-PAGE stained with Coomassie Blue.

Human SmarcAL1 protein fragment - ab162337 from Abcam

Category Protein
Source Wheat germ
Species Human
ab162337 on a 12.5% SDS-PAGE stained with Coomassie Blue.

SMARCAL1 Antibody Blocking Peptide - LS-E12148 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

SMARCAL1 Antibody Blocking Peptide - LS-E12149 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

SMARCAL1 Antibody Blocking Peptide - LS-E14080 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Recombinant Human SmarcAL1 Protein - H00050485-Q01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

Recombinant Human SmarcAL1 Protein - H00050485-P01 from Novus Biologicals

Category Protein
Prices $319.00
Sizes 2 µg
Source Wheat Germ
Species Human

SMARCAL1 / HARP - H00050485-P01 from Acris Antibodies

Category Protein
Prices $310.00
Sizes 2 µg
Species Human

SMARCAL1 / HARP - H00050485-Q01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Source in vitro transl.
Species Human

SMARCAL1 / HARP - H00050485-Q01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Source in vitro transl.
Species Human

SMARCAL1 fusion protein - Ag23707 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50
Source E. coli -derived, PET28a
Species Human

SMARCAL1 fusion protein - Ag3194 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PGEX-4T
Species Human

SMARCAL1 fusion protein - ag0867 from Proteintech Group

Category Protein
Source E. coli-derived, PGEX-4T
Species Human

Recombinant Human SMARCAL1, GST-tagged - SMARCAL1-2806H from Creative Biomart

Category Protein
Source E.coli
Species Human

SmarcAL1 Protein - NBP2-13352PEP from Novus Biologicals

Category Protein
Prices $209.00
Sizes 100 µl
Species Human

HARP-Antibody-Center-Blocking-Peptide - BP6864c from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

SMARCAL1 Peptide, Human - M34GP14727H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (SMARCAL1), partial, Recombinant Protein - MBS1424297 from MyBioSource

Category Protein
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human

Recombinant Human SMARCAL1 Protein, His-tagged - SMARCAL1-23H from Creative Biomart

Category Protein
Source E. coli
Species Human
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