Gene Symbol | TRABD2A |
---|---|
Entrez Gene | 129293 |
Alt Symbol | C2orf89, TIKI1 |
Species | Human |
Gene Type | protein-coding |
Description | TraB domain containing 2A |
Other Description | TRAB domain-containing protein 2A|UPF0632 protein C2orf89|metalloprotease TIKI1 |
Swissprots | I6UMB9 Q86V40 B4DKK8 |
Accessions | EAW99549 EAW99551 EAW99552 Q86V40 AK128325 AK296608 BAG59220 AK309615 BC049209 BC051789 AAH51789 BC073808 BG170846 JQ653415 AFN02881 XM_005264131 XP_005264188 XM_011532504 XP_011530806 NM_001080824 NP_001074293 NM_001277053 NP_001263982 NM_001307978 NP_001294907 |
Function | Metalloprotease that acts as a negative regulator of the Wnt signaling pathway by mediating the cleavage of the 8 N- terminal residues of a subset of Wnt proteins. Following cleavage, Wnt proteins become oxidized and form large disulfide-bond oligomers, leading to their inactivation. Able to cleave WNT3A, WNT5, but not WNT11. Required for head formation. {ECO:0000269|PubMed:22726442}. |
Subcellular Location | Cell membrane {ECO:0000269|PubMed:22726442}; Single-pass type I membrane protein {ECO:0000269|PubMed:22726442}. |
Anti-C2orf89 antibody - ab111443 from Abcam
|
||||||||
Anti-TRABD2A / C2orf89 Antibody (aa300-330, AP) - LS-C262044 from LifeSpan Bioscience
|
||||||||
Anti-TRABD2A / C2orf89 Antibody (aa300-330, APC) - LS-C262046 from LifeSpan Bioscience
|
||||||||
Anti-TRABD2A / C2orf89 Antibody (aa300-330, Biotin) - LS-C262047 from LifeSpan Bioscience
|
||||||||
Anti-TRABD2A / C2orf89 Antibody (aa300-330, FITC) - LS-C262048 from LifeSpan Bioscience
|
||||||||
Anti-TRABD2A / C2orf89 Antibody (aa300-330, Azide-free, HRP) - LS-C262049 from LifeSpan Bioscience
|
||||||||
Anti-TRABD2A / C2orf89 Antibody (aa300-330, PE) - LS-C262050 from LifeSpan Bioscience
|
||||||||
Anti-TRABD2A / C2orf89 Antibody (aa300-330) - LS-C329772 from LifeSpan Bioscience
|
||||||||
Anti-TRABD2A / C2orf89 Antibody (aa342-371) - LS-C165819 from LifeSpan Bioscience
|
||||||||
C2orf89 Polyclonal Antibody - bs-9820R from Bioss
|
||||||||
ANTI-LOC129293 (C-TERM) antibody produced in rabbit - SAB1302188 from Sigma-Aldrich
|
||||||||
LOC129293-Antibody-C-term - AP11741b from Abgent, a WuXi AppTec company
|
||||||||
LOC129293 Antibody - C-terminal region (OAAB07985) - OAAB07985 from Aviva Systems Biology
|
||||||||
Human Tiki1/TRABD2A Antibody - MAB8376 from R&D Systems
|
||||||||
Human Tiki1/TRABD2A MAb (Clone 901705), Mouse IgG2A - MAB8376-SP from R&D Systems
|
||||||||
Anti -LOC129293, CT (C2orf89, UPF0632 protein C2orf89) - 037848 from USBiological Life Science
|
||||||||
Anti -LOC129293, CT (C2orf89, UPF0632 protein C2orf89) (AP) - 037848-AP from USBiological Life Science
|
||||||||
Anti -LOC129293, CT (C2orf89, UPF0632 protein C2orf89) (APC) - 037848-APC from USBiological Life Science
|
||||||||
Anti -LOC129293, CT (C2orf89, UPF0632 protein C2orf89) (Azide free) (HRP) - 037848-HRP from USBiological Life Science
|
||||||||
Anti -LOC129293, CT (C2orf89, UPF0632 protein C2orf89) (Biotin) - 037848-Biotin from USBiological Life Science
|
||||||||
Anti -LOC129293, CT (C2orf89, UPF0632 protein C2orf89) (FITC) - 037848-FITC from USBiological Life Science
|
||||||||
Anti -LOC129293, CT (C2orf89, UPF0632 protein C2orf89) (PE) - 037848-PE from USBiological Life Science
|
||||||||
Rabbit Anti-Human LOC129293 (C-term) - 102-11231 from RayBiotech
|
||||||||
LOC129293 antibody (C-term) - STJ41820 from St John's Laboratory Ltd
|
||||||||
LOC129293, Polyclonal Antibody - MBS642755 from MyBioSource
|