| Gene Symbol |
RRM2
|
| Entrez Gene |
6241
|
| Alt Symbol |
R2, RR2, RR2M
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
ribonucleotide reductase M2
|
| Other Description |
ribonucleoside-diphosphate reductase subunit M2|ribonucleotide reductase M2 polypeptide|ribonucleotide reductase small chain|ribonucleotide reductase small subunit
|
| Swissprots |
P31350 J3KP43 B2R9B5 Q5WRU7
|
| Accessions |
AAD53261 AAK51163 AAX93099 P31350 AK092671 BAG52588 AK123010 BAG53847 AK313719 BAG36462 BC001886 AAH01886 BC028932 AAH28932 BC030154 AAH30154 BM994533 DA477511 DQ891863 ABM82789 DQ895052 ABM85978 S40301 AAA09577 X59618 CAA42181 NM_001034 NP_001025 NM_001165931 NP_001159403
|
| Function |
Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. Inhibits Wnt signaling.
|
| Subcellular Location |
Cytoplasm.
|
| Top Pathways |
p53 signaling pathway, Purine metabolism, Glutathione metabolism, Pyrimidine metabolism
|