RRM2

Gene Symbol RRM2
Entrez Gene 6241
Alt Symbol R2, RR2, RR2M
Species Human
Gene Type protein-coding
Description ribonucleotide reductase M2
Other Description ribonucleoside-diphosphate reductase subunit M2|ribonucleotide reductase M2 polypeptide|ribonucleotide reductase small chain|ribonucleotide reductase small subunit
Swissprots P31350 J3KP43 B2R9B5 Q5WRU7
Accessions AAD53261 AAK51163 AAX93099 P31350 AK092671 BAG52588 AK123010 BAG53847 AK313719 BAG36462 BC001886 AAH01886 BC028932 AAH28932 BC030154 AAH30154 BM994533 DA477511 DQ891863 ABM82789 DQ895052 ABM85978 S40301 AAA09577 X59618 CAA42181 NM_001034 NP_001025 NM_001165931 NP_001159403
Function Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. Inhibits Wnt signaling.
Subcellular Location Cytoplasm.
Top Pathways p53 signaling pathway, Purine metabolism, Glutathione metabolism, Pyrimidine metabolism

p53R2 (C-18) - sc-10843 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
p53R2 (C-18): sc-10843. Western blot analysis of p53R2 expression in non-transfected: sc-117752 (A) and human p53R2 transfected: sc-111702 (B) 293T whole cell lysates.

R2 (A-5) - sc-398294 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
R2 (A-5): sc-398294. Western blot analysis of R2 expression in K-562 (A), SW480 (B) and Jurkat (C) whole cell lysates.

R2 (F-9) - sc-376973 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
R2 (F-9): sc-376973. Western blot analysis of p53R2 expression in non-transfected 293T: sc-117752 (A), human p53R2 transfected 293T: sc-111702 (B) and K-562 (C) whole cell lysates.

R2 (E-16) - sc-10846 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
R2 (E-16): sc-10846. Western blot analysis of R2 expression in HeLa (A), A-431 (B) and K-562 (C) whole cell lysates.

R2 (H-300) - sc-22785 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
R2 (H-300): sc-22785. Western blot analysis of R2 expression in SW480 whole cell lysate.

R2 (I-15) - sc-10848 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
R2 (I-15): sc-10848. Immunofluorescence staining of methanol-fixed HeLa cells showing cytoplasmic staining.

R2 (P-20) - sc-21877 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

R2 (N-18) - sc-10844 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
R2 (N-18): sc-10844. Immunofluorescence staining of methanol-fixed HeLa cells showing cytoplasmic staining.

R2 (SS-22) - sc-81850 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
R2 (SS-22): sc-81850. Western blot analysis of R2 expression in HeLa nuclear extract.

Anti-RRM2 antibody - ab57653 from Abcam

Prices $398.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
RRM2 antibody (ab57653) used in immunohistochemistry at 5ug/ml on formalin fixed and paraffin embedded human stomach.

Anti-RRM2 antibody - ab135583 from Abcam

Prices $376.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-RRM2 antibody (ab135583) at 1/50 dilution + jurkat cell lysate at 35 µg

Anti-RRM2 antibody - ab167583 from Abcam

Prices $376.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
All lanes : Anti-RRM2 antibody (ab167583) at 1/500 dilutionLane 1 : RRM2 transfected lysateLane 2 : Non transfected lysateLysates/proteins at 50 µg per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate secondary antibody at 1/2500 dilution

Anti-RRM2 antibody - ab26170 from Abcam

Prices $376.00
Sizes 50 µg
Host Chicken
Clonality Polyclonal
Anti-RRM2 antibody (ab26170) at 1/2000 dilution + E coli-derived RRM2 fusion protein SecondaryGoat anti-IgY-HRP diluted 1/1000

Anti-RRM2 antibody [1E1] - ab115701 from Abcam

Prices $384.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 1E1
ab115701, at 5 µg/ml, staining RRM2 in Formalin-fixed, Paraffin-embedded Human Kidney tissue by Immunohistochemistry.

Anti-RRM2 antibody [EPR11820] - ab172476 from Abcam

Prices $385.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR11820
All lanes : Anti-RRM2 antibody [EPR11820] (ab172476) at 1/1000 dilutionLane 1 : HeLa cell lysateLane 2 : HepG2 cell lysateLane 3 : K562 cell lysateLane 4 : Jurkat cell lysateLysates/proteins at 10 µg per lane.

Anti-RRM2 antibody - Azide free - ab191800 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-RRM2 antibody - Azide free (ab191800) at 1/1000 dilution + MCF7 whole cell extract at 20 µg

Anti-RRM2 Antibody - LS-C333948 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry of paraffin-embedded human stomach using RRM2 antibody at dilution of 1:200 (200x lens).

Anti-RRM2 Antibody (clone 1E1) IHC-plus™ - LS-B4409 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 1E1
Anti-RRM2 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4409 concentration 5 ug/ml.

Anti-RRM2 Antibody (aa1-111, Azide-free) - LS-C328525 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

Anti-RRM2 Antibody - LS-C341560 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-RRM2 Antibody (aa35-84) - LS-C102203 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
RRM2 antibody LS-C102203 Western blot of Fetal Muscle lysate.

Anti-RRM2 Antibody (aa96-125) - LS-C99351 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin-embedded human skeletal muscle reacted with RRM2 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

RRM2 Antibody (1E1.) - H00006241-M01 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1E1.
Western Blot: RRM2 Antibody (1E1) [H00006241-M01] - RRM2 monoclonal antibody (M01), clone 1E1. Analysis of RRM2 expression in HepG2.

RRM2 Antibody - NBP1-31661 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: RRM2 Antibody [NBP1-31661] - Sample (30 ug of whole cell lysate) A: H1299 10% SDS PAGE; antibody diluted at 1:1000.

RRM2 Antibody - H00006241-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: RRM2 Antibody [H00006241-B01] - RRM2 expression in transfected 293T cell line by RRM2 MaxPab polyclonal antibody (B01). Lane 1: RRM2 transfected lysate (44.90 KDa). Lane 2: Non-transfected lysate.
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