ZC3H12A

Gene Symbol ZC3H12A
Entrez Gene 80149
Alt Symbol MCPIP, MCPIP1, dJ423B22.1
Species Human
Gene Type protein-coding
Description zinc finger CCCH-type containing 12A
Other Description MCP induced protein 1|MCP-1 treatment-induced protein|MCP-induced protein 1|ribonuclease ZC3H12A|zinc finger CCCH domain-containing protein 12A
Swissprots Q9H5P1 D3DPT0 Q5D1E8 Q6I9Z1
Accessions EAX07346 EAX07347 EAX07348 Q5D1E8 AK026884 BAB15581 AK093343 BAG52695 AY920403 AAX14017 BC005001 AAH05001 CR457364 CAG33645 CR995909 DA601465 FJ695517 ACN39723 XM_006710925 XP_006710988 XM_006710926 XP_006710989 XM_011542193 XP_011540495 XM_011542194 XP_011540496 XM_011542195 XP_011540497 XM_011542196 XP_011540498 XM_011542197 XP_011540499 XM_011542198 XP_011540500 NM_025079 NP_079355
Function Has RNase activity and selectively degrades specific target mRNA species. Modulates the immune response and inflammation by regulating the decay of specific mRNA molecules. Recognizes the 3'-untranslated region (UTR) of the mRNA for IL6, CALCR and IL12B. Required for normal decay of IL6 mRNA (By similarity). Triggers apoptosis and promotes angiogenesis in response to the binding of CCL2 to CCR2. Regulates expression of CDH12 and CHD19. {ECO:0000250, ECO:0000269|PubMed:16574901, ECO:0000269|PubMed:18364357, ECO:0000269|PubMed:22561375}.
Subcellular Location Cytoplasm {ECO:0000250}. Nucleus {ECO:0000269|PubMed:16574901}.

MCPIP (P-12) - sc-136750 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
MCPIP (P-12): sc-136750. Immunoperoxidase staining of formalin fixed, paraffin-embedded human adrenal gland tissue showing nuclear and cytoplasmic staining of glandular cells.

Anti-MCPIP1 antibody - ab97910 from Abcam

Prices $384.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-MCPIP1 antibody (ab97910) at 1/1000 dilution + A431 whole cell lysate at 30 µg

Anti-MCPIP1 antibody - ab197976 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-MCPIP1 antibody (ab197976) at 1/200 dilution + K562 cell lysate at 40 µg

Anti-MCPIP1 antibody - ab70681 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-MCPIP1 antibody (ab70681) at 1 µg/mlLane 1 : Heart (Human) Tissue Lysate - adult normal tissue (ab29431)Lane 2 : Spleen (Human) Tissue Lysate - adult normal tissue (ab29699)Lane 3 : Lung (Human) Tissue Lysate (ab4014)Lysates/proteins at 20 µg per lane.SecondaryGoat Anti-Rabbit IgG H&L (HRP) (ab97051) at 1/50000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-MCPIP1 antibody - ab118746 from Abcam

Host Rabbit
Clonality Polyclonal
Anti-MCPIP1 antibody (ab118746) at 1 µg/ml + Human fetal brain lysate at 10 µg

Anti-ZC3H12A / MCPIP1 Antibody (aa331-358, AP) - LS-C273915 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ZC3H12A / MCPIP1 Antibody (aa331-358, APC) - LS-C273917 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ZC3H12A / MCPIP1 Antibody (aa331-358, Biotin) - LS-C273918 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ZC3H12A / MCPIP1 Antibody (aa331-358, FITC) - LS-C273919 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ZC3H12A / MCPIP1 Antibody (aa331-358, Azide-free, HRP) - LS-C273920 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ZC3H12A / MCPIP1 Antibody (aa331-358, PE) - LS-C273921 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ZC3H12A / MCPIP1 Antibody (aa320-369) - LS-C145841 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ZC3H12A / MCPIP antibody LS-C145841 Western blot of Fetal Brain lysate. Antibody concentration 1 ug/ml.

Anti-ZC3H12A / MCPIP1 Antibody (aa331-358) - LS-C326456 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ZC3H12A / MCPIP1 Antibody (aa331-358) IHC-plus™ - LS-B11221 from LifeSpan Bioscience

Prices $395.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
Anti-ZC3H12A / MCPIP1 antibody IHC staining of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B11221 dilution 1:100.

Anti-ZC3H12A / MCPIP1 Antibody (aa241-504) - LS-C186179 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunofluorescence of paraformaldehyde-fixed HeLa using ZC3H12A antibody at 1:200 dilution.

Anti-ZC3H12A / MCPIP1 Antibody (Internal) - LS-C108690 from LifeSpan Bioscience

Prices $325.00, $890.00
Sizes 100 µg, 500 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of ZC3H12A in Raji cell lysate with ZC3H12A antibody at (A) 1 and (B) 2 ug/ml.

MCPIP1/ZC3H12A Antibody (604421) - MAB7875 from Novus Biologicals

Prices $99.00, $259.00
Sizes 25 µg, 100 µg
Host Mouse
Clonality Monoclonal
Clone 604421
Western blot shows lysates of untreated (-) HeLa human cervical epithelial carcinoma cell line and RAW 264.7 mouse monocyte/macrophage cell line and THP‑1 human acute monocytic leukemia cell line untreated (-) or treated (+) with 1 µg/mL LPS for 24 hours or 10 µg/mL LPS for 3 hours, respectively. PVDF membrane was probed with 1 µg/mL of Mouse Anti-Human MCPIP1 Monoclonal Antibody (Catalog # MAB7875) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # HAF018). A specific band was detected for MCPIP1 at approximately 70 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.

MCPIP1/ZC3H12A Antibody - NBP1-83587 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: MCPIP1/ZC3H12A Antibody [NBP1-83587] - Analysis in control (vector only transfected HEK293T lysate) and zC3H12A over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).

MCPIP1/ZC3H12A Antibody - NBP2-37871 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: MCPIP1/ZC3H12A Antibody [NBP2-37871] - Staining of human cell line U-251 MG shows localization to cytoplasmic bodies.

MCPIP1/ZC3H12A Antibody - NBP1-76258 from Novus Biologicals

Prices $329.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-ZC3H12A antibody produced in rabbit - SAB3500391 from Sigma-Aldrich

Prices $348.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-ZC3H12A: <B>Cat. No. SAB3500391</B>: Western blot analysis of ZC3H12A in Raji cell lysate with ZC3H12A antibody at (A) 1 and (B) 2 μg/mL.

ANTI-ZC12A (CENTER) antibody produced in rabbit - SAB1306466 from Sigma-Aldrich

Prices $326.00
Sizes 40 tst
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-ZC12A (Center): <B>Cat. No. SAB1306466</B>: ZC12A Antibody (Center) western blot analysis in HepG2 cell line lysates (35 μg/lane).

Anti-ZC3H12A antibody produced in rabbit - SAB2701079 from Sigma-Aldrich

Prices $326.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Anti-ZC3H12A: <B>Cat. No. SAB2701079</B>: Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using ZC3H12A antibody at 1:200 dilution.

ZC3H12A antibody - C-terminal region (ARP62562_P050) - ARP62562_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ZC3H12A Antibody - middle region (OAAB00998) - OAAB00998 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
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