Gene Symbol | PEBP1 |
---|---|
Entrez Gene | 5037 |
Alt Symbol | HCNP, HCNPpp, HEL-210, HEL-S-34, PBP, PEBP, PEBP-1, RKIP |
Species | Human |
Gene Type | protein-coding |
Description | phosphatidylethanolamine binding protein 1 |
Other Description | Raf kinase inhibitory protein|epididymis luminal protein 210|epididymis secretory protein Li 34|hippocampal cholinergic neurostimulating peptide|neuropolypeptide h3|phosphatidylethanolamine-binding protein 1|prostatic binding protein|prostatic-binding protein|raf kinase inhibitor protein |
Swissprots | B2R4S1 P30086 |
Accessions | EAW98122 EAW98123 P30086 AK226006 AK299414 BAG61396 AK308056 AK311927 BAG34868 BC008714 AAH08714 BC017396 AAH17396 BC018799 BC031102 AAH31102 BF978793 D16111 BAA03684 EU668351 ACF94504 EU794643 ACJ13697 HM131449 ADI99998 S76773 AAD14234 X75252 CAA53031 X85033 CAA59404 NM_002567 NP_002558 |
Function | Binds ATP, opioids and phosphatidylethanolamine. Has lower affinity for phosphatidylinositol and phosphatidylcholine. Serine protease inhibitor which inhibits thrombin, neuropsin and chymotrypsin but not trypsin, tissue type plasminogen activator and elastase (By similarity). Inhibits the kinase activity of RAF1 by inhibiting its activation and by dissociating the RAF1/MEK complex and acting as a competitive inhibitor of MEK phosphorylation. {ECO:0000250, ECO:0000269|PubMed:18294816}. |
Subcellular Location | Cytoplasm {ECO:0000250}. |
RKIP (D42F3) Rabbit mAb - 13006 from Cell Signaling Technology
|
||||||||||
RKIP (G38) Antibody - 5060 from Cell Signaling Technology
|
||||||||||
RKIP Antibody - 4742 from Cell Signaling Technology
|
||||||||||
RKIP (V177) Antibody - 5291 from Cell Signaling Technology
|
||||||||||
RKIP (D-5) - sc-365973 from Santa Cruz Biotechnology
|
||||||||||
RKIP (E-17) - sc-5423 from Santa Cruz Biotechnology
|
||||||||||
RKIP (FL-187) - sc-28837 from Santa Cruz Biotechnology
|
||||||||||
RKIP (G-15) - sc-5422 from Santa Cruz Biotechnology
|
||||||||||
RKIP (H-17) - sc-5426 from Santa Cruz Biotechnology
|
||||||||||
RKIP (8) - sc-101504 from Santa Cruz Biotechnology
|
||||||||||
RKIP (R-17) - sc-5424 from Santa Cruz Biotechnology
|
||||||||||
p-RKIP (hSer 153) - sc-32623 from Santa Cruz Biotechnology
|
||||||||||
p-RKIP (80.Ser 153) - sc-135779 from Santa Cruz Biotechnology
|
||||||||||
p-RKIP (77.Ser 153) - sc-135778 from Santa Cruz Biotechnology
|
||||||||||
Anti-PBP (phospho S153) antibody [EP2845Y] - ab75971 from Abcam
|
||||||||||
Anti-PBP antibody - ab133702 from Abcam
|
||||||||||
Anti-PBP antibody - ab137906 from Abcam
|
||||||||||
Anti-PBP antibody - ab58224 from Abcam
|
||||||||||
Anti-PBP antibody [8] - ab65858 from Abcam
|
||||||||||
Anti-PBP antibody [EPR2875Y] - ab76582 from Abcam
|
||||||||||
Anti-PEBP1 / RKIP Antibody (N-Terminus, FITC) - LS-C281259 from LifeSpan Bioscience
|
||||||||||
Anti-PEBP1 / RKIP Antibody (clone 2G2-1F1) - LS-C197834 from LifeSpan Bioscience
|
||||||||||
Anti-PEBP1 / RKIP Antibody (N-Terminus, Azide-free, HRP) - LS-C281260 from LifeSpan Bioscience
|
||||||||||
Anti-PEBP1 / RKIP Antibody (N-Terminus, PE) - LS-C281261 from LifeSpan Bioscience
|
||||||||||
Anti-PEBP1 / RKIP Antibody (Internal, AP) - LS-C281262 from LifeSpan Bioscience
|