NEDD9

Gene Symbol	NEDD9
Entrez Gene	4739
Alt Symbol	CAS-L, CAS2, CASL, CASS2, HEF1
Species	Human
Gene Type	protein-coding
Description	neural precursor cell expressed, developmentally down-regulated 9
Other Description	Cas scaffolding protein family member 2|Crk-associated substrate related protein Cas-L|Enhancer of filamentation 1 p55|cas-like docking|enhancer of filamentation 1|neural precursor cell expressed developmentally down-regulated protein 9|p130Cas-related protein|renal carcinoma antigen NY-REN-12
Swissprots	Q5XKI0 A8MSJ9 A8K9G7 Q14511 G5E9Y9 Q5T9R4
Accessions	EAW55299 EAW55300 EAW55301 EAW55302 EAW55303 Q14511 AA814628 AJ420493 AK292682 BAF85371 AW963532 BC020686 AAH20686 BC040207 AAH40207 BC050740 BP262776 BX648041 DA660812 DA676780 DA778416 DQ891725 ABM82651 DQ894902 ABM85828 EU832525 ACE87697 EU832607 ACE87009 L43821 AAA98770 U64317 AAB53696 NM_001142393 NP_001135865 NM_001271033 NP_001257962 NM_006403 NP_006394 NM_182966 NP_892011 NR_073131
Function	Docking protein which plays a central coordinating role for tyrosine-kinase-based signaling related to cell adhesion. May function in transmitting growth control signals between focal adhesions at the cell periphery and the mitotic spindle in response to adhesion or growth factor signals initiating cell proliferation. May play an important role in integrin beta-1 or B cell antigen receptor (BCR) mediated signaling in B- and T-cells. Integrin beta-1 stimulation leads to recruitment of various proteins including CRK, NCK and SHPTP2 to the tyrosine phosphorylated form.
Subcellular Location	Cytoplasm, cell cortex. Nucleus. Golgi apparatus. Cell projection, lamellipodium. Cytoplasm. Cell junction, focal adhesion. Note=Localizes to both the cell nucleus and the cell periphery and is differently localized in fibroblasts and epithelial cells. In fibroblasts is predominantly nuclear and in some cells is present in the Golgi apparatus. In epithelial cells localized predominantly in the cell periphery with particular concentration in lamellipodia but is also found in the nucleus. Isoforms p105 and p115 are predominantly cytoplasmic and associate with focal adhesions while p55 associates with mitotic spindle.
Tissue Specificity	Widely expressed. Higher levels detected in kidney, lung, and placenta. Also detected in T-cells, B-cells and diverse cell lines. The protein has been detected in lymphocytes, in diverse cell lines, and in lung tissues.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human HEF1 full length protein - ab132196 from Abcam Category Protein Source Wheat germ Species Human

Human HEF1 peptide - ab39117 from Abcam Category Peptide

NEDD9/CASL/HEF1 Partial Recombinant Protein - H00004739-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human NEDD9/CASL/HEF1 Protein - H00004739-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

NEDD9-Antibody-Center-Blocking-Peptide - BP14592c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

HEF1 blocking peptide - GTX88981-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Dog, Rat

NEDD9 Blocking Peptide - 33R-2070 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

NEDD9 Blocking Peptide - 33R-3816 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

HEF1 Peptide - AC21-1236-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

NEDD9 - H00004739-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

NEDD9 - H00004739-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

NEDD9 - H00004739-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

NEDD9 - H00004739-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

NEDD9 Peptide - 45-940P from ProSci Category Peptide Prices $175.00 Sizes 100 µg Species Human

NEDD9 fusion protein - ag3596 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human NEDD9, His-tagged - NEDD9-29304TH from Creative Biomart Category Protein Source E. coli

Human TRP1 / TYRP1 Protein (His Tag) - 13224-H08B-20 from Sino Biological Category Protein Prices $138.00, $138.00 Sizes 20 µg, 100 µg Source Baculovirus-Insect Cells Species Human

Human TRP1 / TYRP1 Protein (His Tag) - 13224-H08H-20 from Sino Biological Category Protein Prices $138.00, $138.00 Sizes 20 µg, 50 µg Source Human Cells Species Human

Enhancer of filamentation-1 pS369 peptide - pep0725 from Covalab Category Peptide Species Human

Recombinant Human Enhancer of filamentation 1(NEDD9) ,partial - CSB-YP622771HU CSB-EP622771HU CSB-BP622771HU CSB-MP622771HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

NEDD9 (transcript variant 1) - TP307200 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

NEDD9 (transcript variant 3) - TP327437 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

NEDD9, Peptide - MBS425692 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Mouse, Rat, Dog

Recombinant Human TRP1 / TYRP1 Protein (His tag) - PKSH030692 from Elabscience Category Protein Source Human Cell Species Human

Recombinant Human TRP1 / TYRP1 Protein (His tag) - PKSH030693 from Elabscience Category Protein Source Baculovirus-Insect Cells Species Human

Search more