PHC1

Gene Symbol PHC1
Entrez Gene 1911
Alt Symbol EDR1, HPH1, MCPH11, RAE28
Species Human
Gene Type protein-coding
Description polyhomeotic homolog 1 (Drosophila)
Other Description early development regulator 1 (homolog of polyhomeotic 1)|early development regulatory protein 1|polyhomeotic-like 1|polyhomeotic-like protein 1
Swissprots Q9BU63 Q8WVM3 P78364 D3DUV4
Accessions BAA83727 EAW88600 EAW88601 P78364 AB209063 BAD92300 AK293893 BAG57282 BC002871 AAH02871 BC017748 AAH17748 BC073964 AAH73964 BC157850 AAI57851 BM473731 BX640639 CAE45787 CN388283 CN388285 CN388316 U89277 AAC51169 XM_005253334 XP_005253391 XM_011520598 XP_011518900 XM_011520599 XP_011518901 XM_011520600 XP_011518902 XM_011520601 XP_011518903 XM_011520602 XP_011518904 XM_011520603 XP_011518905 NM_004426 NP_004417
Function Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Required for proper control of cellular levels of GMNN expression. {ECO:0000269|PubMed:23418308}.
Subcellular Location Nucleus {ECO:0000269|PubMed:21282530, ECO:0000269|PubMed:9121482}.

PHC1 Antibody - 13505 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from NCCIT and F9 cells using PHC1 Antibody.

PHC1 (1F3F3) Mouse mAb - 13768 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Mouse
Clonality Monoclonal
Clone 1F3F3
Western blot analysis of extracts from various cell lines using PHC1 (1F3F3) Mouse mAb (upper) and GAPDH (D16H11) XP ® Rabbit mAb #5174 (lower). As expected, PHC1 protein is not expressed in DU 145 or NIH/3T3 cells.

PHC1 (D-10) - sc-390880 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
PHC1 (D-10): sc-390880. Western blot analysis of PHC1 expression in F9 whole cell lysate.

PHC1 (P-13) - sc-138523 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
PHC1 (P-13): sc-138523. Western blot analysis of PHC1 expression in F9 whole cell lysate.

PHC1 (L-14) - sc-138522 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-EDR1 / PHC1 antibody - ab102038 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-EDR1 / PHC1 antibody (ab102038) at 1/500 dilution + Human colon tissue lysate at 50 µg

Anti-EDR1 / PHC1 antibody - ab54954 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Western blot against tagged recombinant protein immunogen using ab54954 EDR1 / PHC1 antibody at 1ug/ml.

Anti-EDR1 / PHC1 antibody [1F3F3] - ab175424 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1F3F3
All lanes : Anti-EDR1 / PHC1 antibody [1F3F3] (ab175424) at 1/500 dilutionLane 1 : HEK293 cell lysateLane 2 : EDR1/PHC1 (amino acids 758-1004)-hIgGFc transfected HEK293 cell lysate

Anti-EDR1 / PHC1 antibody - C-terminal - ab166736 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Total extracts from Human HeLa cells were immunoprecipitated (IP) with IgG Lane 1 oranti-EDR1/PHC1 (ab166736) lane 2; followed by WB with ab166736 at room temperature for 2 hours.

Anti-EDR1 / PHC1 antibody - C-terminal - ab178744 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-EDR1 / PHC1 antibody - C-terminal (ab178744) at 1 µg/ml + Human fetal lung lysate at 10 µg

Anti-PHC1 / EDR1 Antibody - LS-C341904 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PHC1 / EDR1 Antibody - LS-C335607 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of various cell lines, using PHC1 antibody.

Anti-PHC1 / EDR1 Antibody (clone 3G1) - LS-C197107 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3G1
PHC1 monoclonal antibody (M05), clone 3G1. Western Blot analysis of PHC1 expression in MCF-7.

Anti-PHC1 / EDR1 Antibody (aa758-1004, clone 1F3F3) - LS-C191851 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1F3F3
Western blot using PHC1 monoclonal antibody against HEK293 (1) and PHC1 (AA: 758-1004)-hIgGFc transfected HEK293 (2) cell lysate.

EDR1/PHC1 Antibody (1F3F3) - NBP2-37371 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1F3F3
Western Blot: EDR1/PHC1 Antibody (1F3F3) [NBP2-37371] - Western blot analysis using PHC1 mAb against HEK293 (1) and PHC1 (AA: 758-1004)-hIgGFc transfected HEK293 (2) cell lysate.

EDR1/PHC1 Antibody - NBP1-84009 from Novus Biologicals

Prices $129.00, $419.00
Sizes 25 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: EDR1/PHC1 Antibody [NBP1-84009] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG. Lane 4: Human Plasma. Lane 5: Human liver tissue. Lane 6: Human tonsil tissue

EDR1/PHC1 Antibody - H00001911-D01P from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: EDR1/PHC1 Antibody [H00001911-D01P] - Analysis of PHC1 expression in human colon.

EDR1/PHC1 Antibody (3G1) - H00001911-M05 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3G1
Western Blot: EDR1/PHC1 Antibody (3G1) [H00001911-M05] - Analysis of PHC1 expression in MCF-7.

EDR1/PHC1 Antibody - H00001911-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

EDR1/PHC1 Polyclonal Antibody - bs-12302R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

EDR1/PHC1 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-12302R-A350 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

EDR1/PHC1 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-12302R-A488 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

EDR1/PHC1 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-12302R-A555 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

EDR1/PHC1 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-12302R-A647 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

EDR1/PHC1 Polyclonal Antibody, Cy3 Conjugated - bs-12302R-Cy3 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Search more