PHC1

Gene Symbol PHC1
Entrez Gene 1911
Alt Symbol EDR1, HPH1, MCPH11, RAE28
Species Human
Gene Type protein-coding
Description polyhomeotic homolog 1 (Drosophila)
Other Description early development regulator 1 (homolog of polyhomeotic 1)|early development regulatory protein 1|polyhomeotic-like 1|polyhomeotic-like protein 1
Swissprots Q9BU63 Q8WVM3 P78364 D3DUV4
Accessions BAA83727 EAW88600 EAW88601 P78364 AB209063 BAD92300 AK293893 BAG57282 BC002871 AAH02871 BC017748 AAH17748 BC073964 AAH73964 BC157850 AAI57851 BM473731 BX640639 CAE45787 CN388283 CN388285 CN388316 U89277 AAC51169 XM_005253334 XP_005253391 XM_011520598 XP_011518900 XM_011520599 XP_011518901 XM_011520600 XP_011518902 XM_011520601 XP_011518903 XM_011520602 XP_011518904 XM_011520603 XP_011518905 NM_004426 NP_004417
Function Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Required for proper control of cellular levels of GMNN expression. {ECO:0000269|PubMed:23418308}.
Subcellular Location Nucleus {ECO:0000269|PubMed:21282530, ECO:0000269|PubMed:9121482}.

PHC1 CRISPR/Cas9 KO Plasmid (h) - sc-408727 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PHC1 HDR Plasmid (h) - sc-408727-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PHC1 Double Nickase Plasmid (h) - sc-408727-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PHC1 Double Nickase Plasmid (h2) - sc-408727-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PHC1 CRISPR Activation Plasmid (h) - sc-408727-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PHC1 CRISPR Activation Plasmid (h2) - sc-408727-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PHC1 Lentiviral Activation Particles (h) - sc-408727-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PHC1 Lentiviral Activation Particles (h2) - sc-408727-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PHC1 siRNA (h) - sc-95881 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PHC1 shRNA Plasmid (h) - sc-95881-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PHC1 shRNA (h) Lentiviral Particles - sc-95881-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

EDR1/PHC1 RNAi - H00001911-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU048761 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

MISSION® esiRNA - EHU108901 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN16711 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16711 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

PHC1 siRNA (Human) - CRH1330 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human PHC1 (NM_004426.2) - SHH374548 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human PHC1(NM_004426.2) - SHR110346 from Creative biogene

Category siRNA
Species Reactivities Human

Human PHC1 siRNA - orb261832 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

PHC1 shRNA Plasmid (Human) - CHH1330 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

PHC1 miRNA 3'UTR clone - MiUTR1H-07841 from Creative biogene

Species Reactivities Human
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