| Gene Symbol |
GAB1
|
| Entrez Gene |
2549
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
GRB2-associated binding protein 1
|
| Other Description |
GRB2-associated binder 1|GRB2-associated-binding protein 1|growth factor receptor bound protein 2-associated protein 1
|
| Swissprots |
Q13480 A8K152 Q6P1W2 Q4W5G2
|
| Accessions |
AAY26398 AAY40964 CCH22599 CCH22600 EAX05072 EAX05073 Q13480 AK022142 BAB13970 AK074381 BAB85065 AK289767 BAF82456 AK295684 BAH12155 AK314635 AL049449 BC030115 BC030751 BC064848 AAH64848 DA109618 DA249555 U43885 AAC50380 XM_005262881 XP_005262938 XM_005262882 XP_005262939 XM_006714167 XP_006714230 XM_006714168 XP_006714231 NM_002039 NP_002030 NM_207123 NP_997006
|
| Function |
Adapter protein that plays a role in intracellular signaling cascades triggered by activated receptor-type kinases. Plays a role in FGFR1 signaling. Probably involved in signaling by the epidermal growth factor receptor (EGFR) and the insulin receptor (INSR).
|
| Top Pathways |
Renal cell carcinoma, ErbB signaling pathway, Neurotrophin signaling pathway, Bacterial invasion of epithelial cells, Proteoglycans in cancer
|
![Western Blot: GAB1 Overexpression Lysate (Adult Normal) [NBL1-10904] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for GAB1.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/3274_GAB1%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-10904-img0002.jpg)