Gene Symbol | GAB1 |
---|---|
Entrez Gene | 2549 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | GRB2-associated binding protein 1 |
Other Description | GRB2-associated binder 1|GRB2-associated-binding protein 1|growth factor receptor bound protein 2-associated protein 1 |
Swissprots | Q13480 A8K152 Q6P1W2 Q4W5G2 |
Accessions | AAY26398 AAY40964 CCH22599 CCH22600 EAX05072 EAX05073 Q13480 AK022142 BAB13970 AK074381 BAB85065 AK289767 BAF82456 AK295684 BAH12155 AK314635 AL049449 BC030115 BC030751 BC064848 AAH64848 DA109618 DA249555 U43885 AAC50380 XM_005262881 XP_005262938 XM_005262882 XP_005262939 XM_006714167 XP_006714230 XM_006714168 XP_006714231 NM_002039 NP_002030 NM_207123 NP_997006 |
Function | Adapter protein that plays a role in intracellular signaling cascades triggered by activated receptor-type kinases. Plays a role in FGFR1 signaling. Probably involved in signaling by the epidermal growth factor receptor (EGFR) and the insulin receptor (INSR). |
Top Pathways | Renal cell carcinoma, ErbB signaling pathway, Neurotrophin signaling pathway, Bacterial invasion of epithelial cells, Proteoglycans in cancer |