Gene Symbol | GAB1 |
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Entrez Gene | 2549 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | GRB2-associated binding protein 1 |
Other Description | GRB2-associated binder 1|GRB2-associated-binding protein 1|growth factor receptor bound protein 2-associated protein 1 |
Swissprots | Q13480 A8K152 Q6P1W2 Q4W5G2 |
Accessions | AAY26398 AAY40964 CCH22599 CCH22600 EAX05072 EAX05073 Q13480 AK022142 BAB13970 AK074381 BAB85065 AK289767 BAF82456 AK295684 BAH12155 AK314635 AL049449 BC030115 BC030751 BC064848 AAH64848 DA109618 DA249555 U43885 AAC50380 XM_005262881 XP_005262938 XM_005262882 XP_005262939 XM_006714167 XP_006714230 XM_006714168 XP_006714231 NM_002039 NP_002030 NM_207123 NP_997006 |
Function | Adapter protein that plays a role in intracellular signaling cascades triggered by activated receptor-type kinases. Plays a role in FGFR1 signaling. Probably involved in signaling by the epidermal growth factor receptor (EGFR) and the insulin receptor (INSR). |
Top Pathways | Renal cell carcinoma, ErbB signaling pathway, Neurotrophin signaling pathway, Bacterial invasion of epithelial cells, Proteoglycans in cancer |
Gab 1 CRISPR/Cas9 KO Plasmid (h) - sc-401108 from Santa Cruz Biotechnology
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Gab 1 HDR Plasmid (h) - sc-401108-HDR from Santa Cruz Biotechnology
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Gab 1 Double Nickase Plasmid (h) - sc-401108-NIC from Santa Cruz Biotechnology
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Gab 1 Double Nickase Plasmid (h2) - sc-401108-NIC-2 from Santa Cruz Biotechnology
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Gab 1 CRISPR Activation Plasmid (h) - sc-401108-ACT from Santa Cruz Biotechnology
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Gab 1 CRISPR Activation Plasmid (h2) - sc-401108-ACT-2 from Santa Cruz Biotechnology
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Gab 1 Lentiviral Activation Particles (h) - sc-401108-LAC from Santa Cruz Biotechnology
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Gab 1 Lentiviral Activation Particles (h2) - sc-401108-LAC-2 from Santa Cruz Biotechnology
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Gab 1 siRNA (h) - sc-35431 from Santa Cruz Biotechnology
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Gab 1 shRNA Plasmid (h) - sc-35431-SH from Santa Cruz Biotechnology
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Gab 1 shRNA (h) Lentiviral Particles - sc-35431-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU077111 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN9038 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9038 from Sigma-Aldrich
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GAB1 siRNA (Human) - CRH1688 from Cohesion Biosciences
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GAB1 RNAi - H00002549-R01 from Novus Biologicals
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GAB1 - MBS8230760 from MyBioSource
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shRNA set against Human GAB1 (NM_002039.3) - SHH298309 from Creative biogene
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Human GAB1 siRNA - orb262190 from Biorbyt
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GAB1 shRNA Plasmid (Human) - CHH1688 from Cohesion Biosciences
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GAB1 miRNA 3'UTR clone - MiUTR1H-03898 from Creative biogene
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GAB1 miRNA 3'UTR clone - MiUTR1H-03899 from Creative biogene
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