PTK7

Gene Symbol	PTK7
Entrez Gene	5754
Alt Symbol	CCK-4, CCK4
Species	Human
Gene Type	protein-coding
Description	protein tyrosine kinase 7 (inactive)
Other Description	PTK7 protein tyrosine kinase 7|colon carcinoma kinase 4|inactive tyrosine-protein kinase 7|pseudo tyrosine kinase receptor 7|tyrosine-protein kinase-like 7
Swissprots	Q8NFA5 Q13417 Q8NFA8 A8K974 Q6IQ54 Q5T650 Q8NFA7 B7Z477 E9PFZ5 Q8NFA6 Q13308
Accessions	AAL39062 EAX04154 EAX04155 EAX04156 EAX04157 EAX04158 EAX04159 EAX04160 Q13308 AB209350 BAD92587 AF531868 AAN04862 AF531869 AAN04863 AF531870 AAN04864 AF531871 AAN04865 AF531872 AAN04866 AI140260 AK055648 BAG51548 AK093428 AK097717 AK131487 AK291016 BAF83705 AK292589 BAF85278 AK296931 BAH12457 AK296953 BAH12463 AL157486 CAB75674 BC002377 BC014626 BC046109 AAH46109 BC071557 AAH71557 BM811107 BQ881986 CA389442 CN266652 DA048438 U33635 AAA87565 U40271 AAC50484 XM_011514765 XP_011513067 XM_011514766 XP_011513068 XR_926286 NM_001270398 NP_001257327 NM_002821 NP_002812 NM_152880 NP_690619 NM_152881 NP_690620 NM_152882 NP_690621 NR_072997 NR_072998 NM_152883
Function	Inactive tyrosine kinase involved in Wnt signaling pathway. Component of both the non-canonical (also known as the Wnt/planar cell polarity signaling) and the canonical Wnt signaling pathway. Functions in cell adhesion, cell migration, cell polarity, proliferation, actin cytoskeleton reorganization and apoptosis. Has a role in embryogenesis, epithelial tissue organization and angiogenesis. {ECO:0000269|PubMed:18471990, ECO:0000269|PubMed:20558616, ECO:0000269|PubMed:20837484, ECO:0000269|PubMed:21103379, ECO:0000269|PubMed:21132015}.
Subcellular Location	Membrane {ECO:0000269|PubMed:20837484}; Single-pass type I membrane protein {ECO:0000269|PubMed:20837484}. Cell junction {ECO:0000269|PubMed:20837484}. Note=Colocalizes with MMP14 at cell junctions. Also localizes at the leading edge of migrating cells.
Tissue Specificity	Highly expressed in lung, liver, pancreas, kidney, placenta and melanocytes. Weakly expressed in thyroid gland, ovary, brain, heart and skeletal muscle. Also expressed in erythroleukemia cells. But not expressed in colon.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human CCK4 protein fragment - ab114772 from Abcam Category Protein Prices $420.00 Sizes 10 µg Source Wheat germ Species Human

CCK4 / PTK7 Antibody Blocking Peptide - LS-E30378 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

CCK4 / PTK7 Antibody Blocking Peptide - LS-E30379 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

CCK4 / PTK7 Antibody Blocking Peptide - LS-E9269 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human PTK7/CCK4 Protein - H00005754-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

PTK7/CCK4 Blocking Peptide - NBP1-76819PEP from Novus Biologicals Category Peptide Prices $129.00 Sizes 50 µg Species Human

PTK7/CCK4 Blocking Peptide - NBP1-76820PEP from Novus Biologicals Category Peptide Prices $129.00 Sizes 50 µg Species Human

PTK7/CCK4 Peptide - P2800 from Novus Biologicals Category Peptide Species Human

CCK4-PTK7-Antibody-N-term-Blocking-peptide - BP7800a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Human PTK7 protein - orb246157 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

Human CCK4 Protein - abx065877 from Abbexa Category Protein Source E.coli Species Human

PTK7 / CCK4 - H00005754-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

PTK7 / CCK4 - H00005754-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

PTK7 / CCK4 Control Peptide - AP30699CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

PTK7 / CCK4 Control Peptide - AP30700CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

Cholecystokinin 4, Tetrapeptide (CCK4), Human - 20-6613 from ARP American Research Products Category Protein Prices $449.00 Sizes 50 µg Source E.coli Species Human

Cholecystokinin 4, Tetrapeptide (CCK4), Human - 20-6614 from ARP American Research Products Category Protein Prices $449.00 Sizes 50 µg Source E.coli Species Human

PTK7 Peptide - 4299P from ProSci Category Peptide Species Human

PTK7 Peptide - 4297P from ProSci Category Peptide Species Human

PTK7 fusion protein - ag12026 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

PTK7 fusion protein - Ag12004 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human PTK7 - PTK7-27862TH from Creative Biomart Category Protein Source Wheat germ

Recombinant Human PTK7, GST-tagged - PTK7-183H from Creative Biomart Category Protein Source Sf9 insect cells using baculovirus Species Human

Recombinant Cholecystokinin 4, Tetrapeptide (CCK4) - RPA378Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

PTK7 protein-GST fusion - 009-001-T09 from Rockland Immunochemicals Inc Category Protein Prices $499.00 Sizes 50 µg Species Human

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