PTK7

Gene Symbol PTK7
Entrez Gene 5754
Alt Symbol CCK-4, CCK4
Species Human
Gene Type protein-coding
Description protein tyrosine kinase 7 (inactive)
Other Description PTK7 protein tyrosine kinase 7|colon carcinoma kinase 4|inactive tyrosine-protein kinase 7|pseudo tyrosine kinase receptor 7|tyrosine-protein kinase-like 7
Swissprots Q8NFA5 Q13417 Q8NFA8 A8K974 Q6IQ54 Q5T650 Q8NFA7 B7Z477 E9PFZ5 Q8NFA6 Q13308
Accessions AAL39062 EAX04154 EAX04155 EAX04156 EAX04157 EAX04158 EAX04159 EAX04160 Q13308 AB209350 BAD92587 AF531868 AAN04862 AF531869 AAN04863 AF531870 AAN04864 AF531871 AAN04865 AF531872 AAN04866 AI140260 AK055648 BAG51548 AK093428 AK097717 AK131487 AK291016 BAF83705 AK292589 BAF85278 AK296931 BAH12457 AK296953 BAH12463 AL157486 CAB75674 BC002377 BC014626 BC046109 AAH46109 BC071557 AAH71557 BM811107 BQ881986 CA389442 CN266652 DA048438 U33635 AAA87565 U40271 AAC50484 XM_011514765 XP_011513067 XM_011514766 XP_011513068 XR_926286 NM_001270398 NP_001257327 NM_002821 NP_002812 NM_152880 NP_690619 NM_152881 NP_690620 NM_152882 NP_690621 NR_072997 NR_072998 NM_152883
Function Inactive tyrosine kinase involved in Wnt signaling pathway. Component of both the non-canonical (also known as the Wnt/planar cell polarity signaling) and the canonical Wnt signaling pathway. Functions in cell adhesion, cell migration, cell polarity, proliferation, actin cytoskeleton reorganization and apoptosis. Has a role in embryogenesis, epithelial tissue organization and angiogenesis. {ECO:0000269|PubMed:18471990, ECO:0000269|PubMed:20558616, ECO:0000269|PubMed:20837484, ECO:0000269|PubMed:21103379, ECO:0000269|PubMed:21132015}.
Subcellular Location Membrane {ECO:0000269|PubMed:20837484}; Single-pass type I membrane protein {ECO:0000269|PubMed:20837484}. Cell junction {ECO:0000269|PubMed:20837484}. Note=Colocalizes with MMP14 at cell junctions. Also localizes at the leading edge of migrating cells.
Tissue Specificity Highly expressed in lung, liver, pancreas, kidney, placenta and melanocytes. Weakly expressed in thyroid gland, ovary, brain, heart and skeletal muscle. Also expressed in erythroleukemia cells. But not expressed in colon.

PTK7 Antibody - 11926 from Cell Signaling Technology

Prices $239.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from various cell lines using PTK7 Antibody.

CCK-4 (C-14) - sc-46305 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

CCK-4 (H-300) - sc-292650 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

CCK-4 (K-14) - sc-46306 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

CCK-4 (N-18) - sc-46308 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CCK-4 (N-18): sc-46308. Immunoperoxidase staining of formalin fixed, paraffin-embedded human pre-menopausal uterus tissue showing cytoplasmic staining of glandular cells.

CCK-4 (WW02) - sc-100304 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
CCK-4 (WW02): sc-100304. Western blot analysis of CCK-4 expression in A-431 whole cell lysate.

Anti-CCK4 antibody - ab62074 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ab62074 staining CCK4 in E9.5 mouse embryo tissue sections by Immunohistochemistry (IHC-Fr - frozen sections). Tissue was fixed with paraformaldehyde, permeabilized with 0.1% Triton X-100 in PBS and blocked with 5% serum for 1 hour at 25°C. Samples were incubated with primary antibody (1/500 in 5% donkey serum) for 12 hours at 4°C. An Alexa Fluor® 488-conjugated donkey anti-rabbit IgG polyclonal (1/1000) was used as the secondary antibody.Image shows sagittal section of E9.5 mouse embryo. Neuroectoderm and underlying mesoderm labelled with ab62074 in green. DAPI stained nuclei in blue.See Abreview

Anti-CCK4 antibody - ab62073 from Abcam

Host Rabbit
Clonality Polyclonal
All lanes : Anti-CCK4 antibody (ab62073) at 1 µg/mlLane 1 : Human colon tissue lysateLane 2 : Mouse kidney tissue lysateLane 3 : Rat liver tissue lysateLysates/proteins at 10 µg per lane.Secondaryanti-rabbit IgG

Anti-CCK4 antibody - ab117412 from Abcam

Prices $370.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ab117412 staining CCK4 (green) in wild type mouse embryonic stem cells (D3) by ICC/IF (Immunocytochemistry/immunofluorescence). Cells were fixed with methanol/acetone (1:1), permeabilized with 0.1% Triton X-100 and blocked with 1% serum for 30 minutes at 16°C. Samples were incubated with primary antibody (1/100 in blocking buffer) for 2 hour at 16°C. ab15007, an Alexa Fluor® 488-conjugated goat anti-rabbit IgG polyclonal (1/200) was used as the secondary antibody. DAPI (blue) - nuclei.See Abreview

Anti-CCK4 antibody - ab88077 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Anti-CCK4 antibody (ab88077) at 5 µg/ml + recombinant protein (immunogen) at 0.2 µgSecondaryGoat anti-mouse IgG (H&L)-HRP conjugate at 1/5000 dilution

Anti-CCK4 antibody - ab55633 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-CCK4 antibody [2E7] - ab119310 from Abcam

Prices $370.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2E7
All lanes : Anti-CCK4 antibody [2E7] (ab119310) at 1/500 dilutionLane 1 : HEK293T cell lysate transfected with pCMV6-ENTRY control cDNALane 2 : HEK293T cell lysate transfected with pCMV6-ENTRY CCK4 cDNALysates/proteins at 5 µg per lane.

Anti-CCK4 antibody [4F9] - ab104839 from Abcam

Host Mouse
Clonality Monoclonal
Clone 4F9
All lanes : Anti-CCK4 antibody [4F9] (ab104839) at 1/500 dilutionLane 1 : HeLa cell lysateLane 2 : A431 cell lysateLane 3 : HCT116 cell lysateLane 4 : Caco2 cell lysateLane 5 : HepG2 cell lysateLane 6 : MCF-7 cell lysate

Anti-CCK4 antibody - N-terminal - ab135675 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-CCK4 antibody - N-terminal (ab135675) at 1/50 dilutionLane 1 : Non-transfected 293 cell lysate Lane 2 : 293 cell lysate transiently transfected with the CCK4 geneLysates/proteins at 2 µg per lane.

Anti-CCK4 / PTK7 Antibody (aa31-199) - LS-C79252 from LifeSpan Bioscience

Prices $605.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-CCK4 / PTK7 Antibody (N-Terminus) - LS-C144696 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-CCK4 / PTK7 Antibody (N-Terminus) - LS-C153467 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-CCK4 / PTK7 Antibody - LS-C155111 from LifeSpan Bioscience

Prices $245.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-CCK4 / PTK7 Antibody (aa900-950) - LS-C191238 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-CCK4 / PTK7 Antibody (N-Terminus, AP) - LS-C206432 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CCK4 / PTK7 Antibody (N-Terminus, APC) - LS-C206433 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CCK4 / PTK7 Antibody (N-Terminus, Biotin) - LS-C206434 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CCK4 / PTK7 Antibody (N-Terminus, FITC) - LS-C206435 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CCK4 / PTK7 Antibody (aa36-146, APC) - LS-C206844 from LifeSpan Bioscience

Prices $680.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal

Anti-CCK4 / PTK7 Antibody (N-Terminus, PE) - LS-C206438 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
Search more