| Gene Symbol | YAF2 |
|---|---|
| Entrez Gene | 10138 |
| Alt Symbol | - |
| Species | Human |
| Gene Type | protein-coding |
| Description | YY1 associated factor 2 |
| Other Description | YY1-associated factor 2 |
| Swissprots | Q99710 Q8IY57 B4DFU3 A8K5P0 G3V465 |
| Accessions | EAW57834 EAW57835 EAW57836 EAW57837 EAW57838 EAW57839 EAW57840 Q8IY57 AA789222 AI654632 AK127531 AK291355 BAF84044 AK294260 BAG57554 AK296191 BAG58921 BC037777 AAH37777 BX649019 DA011078 DA491895 EU446625 ABZ92154 EU446756 ABZ92285 XM_006719184 XP_006719247 XM_006719185 XP_006719248 XM_011537728 XP_011536030 XM_011537729 XP_011536031 XR_245886 XR_944464 XR_944466 XR_944467 XR_944468 XR_944469 XR_944470 NM_001190977 NP_001177906 NM_001190979 NP_001177908 NM_001190980 NP_001177909 NM_005748 NP_005739 NR_034000 NM_001012424 |
| Function | Binds to MYC and inhibits MYC-mediated transactivation. Also binds to MYCN and enhances MYCN-dependent transcriptional activation. Increases calpain 2-mediated proteolysis of YY1 in vitro. Component of the E2F6.com-1 complex, a repressive complex that methylates 'Lys-9' of histone H3, suggesting that it is involved in chromatin-remodeling. {ECO:0000269|PubMed:11593398, ECO:0000269|PubMed:12706874, ECO:0000269|PubMed:9016636}. |
| Subcellular Location | Nucleus {ECO:0000269|PubMed:11593398}. |
YAF2 - MBS1273948 from MyBioSource
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human YAF2 ORF clone - CDCH101944 from Creative Biomart
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human YAF2 ORF clone - CDCH101945 from Creative Biomart
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human YAF2 ORF clone - CDCH101946 from Creative Biomart
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human YAF2 ORF clone - CDCH101947 from Creative Biomart
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human YAF2 ORF clone - CDCH101948 from Creative Biomart
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human YAF2 ORF clone - CDCH101949 from Creative Biomart
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human YAF2 ORF clone - CDCH101950 from Creative Biomart
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human YAF2 ORF clone - CDCH101951 from Creative Biomart
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Human YAF2 ORF Clone(NM_001190977.1) - CDCL181467 from Creative Biomart
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Human YAF2 ORF Clone(NM_005748.4) - CDCL181468 from Creative Biomart
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Human YAF2 ORF Clone(NM_001190977.1) - CDCR358112 from Creative Biomart
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Human YAF2 ORF Clone(NM_001190979.1) - CDCR358113 from Creative Biomart
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Human YAF2 ORF Clone(NM_001190979.1) - CDCR358114 from Creative Biomart
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Human YAF2 ORF Clone(NM_001190980.1) - CDCR358115 from Creative Biomart
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Human YAF2 ORF Clone(NM_001190980.1) - CDCR358116 from Creative Biomart
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Human YAF2 ORF Clone(NM_001190977.1) - CDCR358117 from Creative Biomart
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Human YAF2 ORF Clone(NM_001190979.1) - CDCR358113 from Creative biogene
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human YAF2 ORF clone (NM_001190977.1) - CDCH101946 from Creative biogene
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human YAF2 ORF clone (NM_001190980.1) - CDCH101948 from Creative biogene
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Human YAF2 ORF Clone (BC037777) - CDCS409228 from Creative biogene
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