Gene Symbol | YAF2 |
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Entrez Gene | 10138 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | YY1 associated factor 2 |
Other Description | YY1-associated factor 2 |
Swissprots | Q99710 Q8IY57 B4DFU3 A8K5P0 G3V465 |
Accessions | EAW57834 EAW57835 EAW57836 EAW57837 EAW57838 EAW57839 EAW57840 Q8IY57 AA789222 AI654632 AK127531 AK291355 BAF84044 AK294260 BAG57554 AK296191 BAG58921 BC037777 AAH37777 BX649019 DA011078 DA491895 EU446625 ABZ92154 EU446756 ABZ92285 XM_006719184 XP_006719247 XM_006719185 XP_006719248 XM_011537728 XP_011536030 XM_011537729 XP_011536031 XR_245886 XR_944464 XR_944466 XR_944467 XR_944468 XR_944469 XR_944470 NM_001190977 NP_001177906 NM_001190979 NP_001177908 NM_001190980 NP_001177909 NM_005748 NP_005739 NR_034000 NM_001012424 |
Function | Binds to MYC and inhibits MYC-mediated transactivation. Also binds to MYCN and enhances MYCN-dependent transcriptional activation. Increases calpain 2-mediated proteolysis of YY1 in vitro. Component of the E2F6.com-1 complex, a repressive complex that methylates 'Lys-9' of histone H3, suggesting that it is involved in chromatin-remodeling. {ECO:0000269|PubMed:11593398, ECO:0000269|PubMed:12706874, ECO:0000269|PubMed:9016636}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:11593398}. |
Human YY1 associated factor 2 full length protein - ab160834 from Abcam
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Human YY1 associated factor 2 protein fragment - ab160835 from Abcam
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YAF2 Antibody Blocking Peptide - LS-E11484 from LifeSpan Bioscience
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YAF2 Antibody Blocking Peptide - LS-E10998 from LifeSpan Bioscience
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Recombinant Human YAF2 Protein - H00010138-Q01 from Novus Biologicals
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Recombinant Human YAF2 Protein - H00010138-P01 from Novus Biologicals
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YAF2 Blocking Peptide - abx064233 from Abbexa
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YAF2 - H00010138-P01-10 from Acris Antibodies
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YAF2 - H00010138-P01-25 from Acris Antibodies
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YAF2 - H00010138-Q01-10 from Acris Antibodies
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YAF2 - H00010138-Q01-25 from Acris Antibodies
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YAF2 fusion protein - Ag5444 from Proteintech Group
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YAF2 fusion protein - Ag5023 from Proteintech Group
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Recombinant Human YAF2, His-tagged - YAF2-3760H from Creative Biomart
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YAF2 Blocking Peptide - CBP3039 from Cohesion Biosciences
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Recombinant Human YY1-associated factor 2(YAF2) - CSB-YP810297HU CSB-EP810297HU CSB-BP810297HU CSB-MP810297HU from Cusabio
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YAF2 - TP314071 from Acris Antibodies
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YY1-associated factor 2 (YAF2) , Recombinant Protein - MBS1361833 from MyBioSource
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Recombinant YY1 Associated Factor 2 (YAF2) - RPC610Hu01 from Uscn Life Science Inc.
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Recombinant YY1 Associated Factor 2 (YAF2) - RPC610Mu01 from Uscn Life Science Inc.
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Recombinant YY1 Associated Factor 2 (YAF2) - RPC610Ra01 from Uscn Life Science Inc.
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Recombinant YY1 Associated Factor 2 (YAF2) - RPC610Hu01 from Cloud-clone
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YAF2 Recombinant Protein Antigen - NBP1-89444PEP from Novus Biologicals
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YAF2 Peptide, Human - M34GP17608H from Creative Peptides
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Recombinant YY1 Associated Factor 2 (YAF2) - RPU51564 from Biomatik
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