MUC20

Gene Symbol	MUC20
Entrez Gene	200958
Alt Symbol	MUC-20
Species	Human
Gene Type	protein-coding
Description	mucin 20, cell surface associated
Other Description	mucin-20|transmembrane mucin MUC20S
Swissprots	Q76I85 Q6UX97 Q8N307 Q96KA1 Q86ST8 Q9P2I8 Q76I83 Q8NBY6
Accessions	AFH78580 AFH78584 AFI24895 AFI24896 BAD06720 EAW78022 Q8N307 AB037780 BAA92597 AB098731 BAD06718 AK027314 BAB55035 AK075138 BAC11428 AK298316 BAH12755 AK311504 AY358449 AAQ88814 BC029267 AAH29267 BC044243 AAH44243 BF883124 BM697386 BM721408 BM986861 BP352469 BU685426 DC348309 HG496572 HG496581 HG496582 HG496583 JF432240 ADZ15457 NM_001282506 NP_001269435 NM_001291833 NP_001278762 NM_020790 NP_065841 NM_152673 NP_689886 NM_001098516
Function	May regulate MET signaling cascade. Seems to decrease hepatocyte growth factor (HGF)-induced transient MAPK activation. Blocks GRB2 recruitment to MET thus suppressing the GRB2-RAS pathway. Inhibits HGF-induced proliferation of MMP1 and MMP9 expression. {ECO:0000269|PubMed:15314156}.
Subcellular Location	Secreted {ECO:0000305}. Apical cell membrane {ECO:0000269|PubMed:14565953}. Basolateral cell membrane {ECO:0000269|PubMed:14565953}. Cell projection, microvillus membrane {ECO:0000269|PubMed:14565953}.
Tissue Specificity	Highly expressed in kidney, moderately in placenta, lung, prostate, liver, and digestive system. In the kidney, localized in the proximal tubules but not in the glomerulus or distal tubules. Detected in most of the male urogenital tract epithelia, with the exception of epididymis. {ECO:0000269|PubMed:14565953, ECO:0000269|PubMed:16997931}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human MUC20 full length protein - ab165875 from Abcam Category Protein Source Wheat germ Species Human

Recombinant Human MUC20 Protein - H00200958-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Source Wheat Germ Species Human

Mucin-20 - H00200958-P01 from Acris Antibodies Category Protein Prices $340.00 Sizes 2 µg Species Human

MUC20 fusion protein - ag4205 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human MUC20, GST-tagged - MUC20-1108H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Mucin 20 (MUC20) - RPA995Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Mucin 20 (MUC20) - RPA995Ra01 from Uscn Life Science Inc. Category Protein Source E.coli Species Rat

Recombinant Human Mucin-20(MUC20) - CSB-YP822693HU CSB-EP822693HU CSB-BP822693HU CSB-MP822693HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

MUC20-Blocking-Peptide-C-term - BP7830b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

MUC20-Blocking-Peptide-N-term - BP7830a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

MUC20 Peptide, Human - M34GP09933H from Creative Peptides Category Peptide Source Synthetic. Species Human

Mucin 20, Recombinant Protein - MBS2031435 from MyBioSource Category Protein Prices $195.00, $420.00, $650.00 Sizes 10 µg, 50 µg, 100 µg Source Prokaryotic expression Species Rat

Mucin-20 (MUC20), Recombinant Protein - MBS1408277 from MyBioSource Category Protein Prices $1,490.00, $1,490.00, $1,715.00, $1,715.00, $2,540.00, $2,540.00, $2,980.00, $2,980.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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