MUC20

Gene Symbol MUC20
Entrez Gene 200958
Alt Symbol MUC-20
Species Human
Gene Type protein-coding
Description mucin 20, cell surface associated
Other Description mucin-20|transmembrane mucin MUC20S
Swissprots Q76I85 Q6UX97 Q8N307 Q96KA1 Q86ST8 Q9P2I8 Q76I83 Q8NBY6
Accessions AFH78580 AFH78584 AFI24895 AFI24896 BAD06720 EAW78022 Q8N307 AB037780 BAA92597 AB098731 BAD06718 AK027314 BAB55035 AK075138 BAC11428 AK298316 BAH12755 AK311504 AY358449 AAQ88814 BC029267 AAH29267 BC044243 AAH44243 BF883124 BM697386 BM721408 BM986861 BP352469 BU685426 DC348309 HG496572 HG496581 HG496582 HG496583 JF432240 ADZ15457 NM_001282506 NP_001269435 NM_001291833 NP_001278762 NM_020790 NP_065841 NM_152673 NP_689886 NM_001098516
Function May regulate MET signaling cascade. Seems to decrease hepatocyte growth factor (HGF)-induced transient MAPK activation. Blocks GRB2 recruitment to MET thus suppressing the GRB2-RAS pathway. Inhibits HGF-induced proliferation of MMP1 and MMP9 expression. {ECO:0000269|PubMed:15314156}.
Subcellular Location Secreted {ECO:0000305}. Apical cell membrane {ECO:0000269|PubMed:14565953}. Basolateral cell membrane {ECO:0000269|PubMed:14565953}. Cell projection, microvillus membrane {ECO:0000269|PubMed:14565953}.
Tissue Specificity Highly expressed in kidney, moderately in placenta, lung, prostate, liver, and digestive system. In the kidney, localized in the proximal tubules but not in the glomerulus or distal tubules. Detected in most of the male urogenital tract epithelia, with the exception of epididymis. {ECO:0000269|PubMed:14565953, ECO:0000269|PubMed:16997931}.

Mucin 20 CRISPR/Cas9 KO Plasmid (h) - sc-415003 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Mucin 20 HDR Plasmid (h) - sc-415003-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Mucin 20 Double Nickase Plasmid (h) - sc-415003-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Mucin 20 Double Nickase Plasmid (h2) - sc-415003-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Mucin 20 CRISPR Activation Plasmid (h) - sc-415003-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Mucin 20 CRISPR Activation Plasmid (h2) - sc-415003-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Mucin 20 Lentiviral Activation Particles (h) - sc-415003-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Mucin 20 Lentiviral Activation Particles (h2) - sc-415003-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Mucin 20 siRNA (h) - sc-78155 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Mucin 20 shRNA Plasmid (h) - sc-78155-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Mucin 20 shRNA (h) Lentiviral Particles - sc-78155-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU120311 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN14757 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND14757 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MUC20 siRNA (Human) - CRJ6272 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human MUC20 (NM_152673.2) - SHH346904 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human MUC20(NM_152673.2) - SHH208379 from Creative biogene

Category siRNA
Species Reactivities Human

Human MUC20 siRNA - orb276773 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

MUC20 shRNA Plasmid (Human) - CHJ6272 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

MUC20 miRNA 3'UTR clone - MiUTR1H-06531 from Creative biogene

Species Reactivities Human
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