| Gene Symbol |
CXXC1
|
| Entrez Gene |
30827
|
| Alt Symbol |
2410002I16Rik, 5830420C16Rik, CFP1, CGBP, HsT2645, PCCX1, PHF18, SPP1, ZCGPC1, hCGBP
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
CXXC finger protein 1
|
| Other Description |
CXXC finger 1 (PHD domain)|CXXC-type zinc finger protein 1|CpG binding protein|DNA-binding protein with PHD finger and CXXC domain|PHD finger and CXXC domain-containing protein 1|cpG-binding protein|zinc finger, CpG binding-type containing 1
|
| Swissprots |
Q9P2V7 Q96BC8 Q8N2W4 B2RC03 Q9P0U4
|
| Accessions |
EAW62968 EAW62969 EAW62970 Q9P0U4 AA236925 AB031069 BAA96307 AB209883 BAD93120 AF149758 AAF37799 AK294645 BAG57822 AK314886 BAG37400 AL136862 CAB66796 BC002504 BC009188 BC014940 AAH14940 BC015733 AAH15733 BC029922 AAH29922 BX647189 DQ890630 ABM92247 DQ893798 ABM84724 XM_011525940 XP_011524242 XM_011525941 XP_011524243 NM_001101654 NP_001095124 NM_014593 NP_055408
|
| Function |
Transcriptional activator that exhibits a unique DNA binding specificity for CpG unmethylated motifs with a preference for CpGG. {ECO:0000269|PubMed:21407193}.
|
| Subcellular Location |
Nucleus speckle {ECO:0000269|PubMed:12200428, ECO:0000269|PubMed:17355966}. Note=Associated with euchromatin. During mitosis, excluded from condensed chromosomes.
|
| Tissue Specificity |
Ubiquitous.
|
![Western Blot: CXXC1 Overexpression Lysate (Adult Normal) [NBL1-09648] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for CXXC1.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/4833_CXXC1%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-09648-img0002.jpg)